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Warfarin News (14 articles)



Apixaban Superior to Warfarin Across Wide Range of Patient Risk Scores

A new anticoagulant called apixaban is superior to warfarin in preventing stroke with consistent effects across a wide range of stroke and bleeding risk in patients with atrial fibrillation, according to Duke University Medical Center researchers. Their results, published online in The...

Published on 3 October 2012, 02:08


Safety Indicators Confirmed for Common Treatment of Heart Defect

A new study by medical scientists coordinated from the University of Manchester has for the first time used patients’ results to establish that “safety indicators” for people taking anticoagulant drugs to regulate a common heart condition are correct.More than 760,000 patients in the UK...

Published on 3 July 2012, 05:55


Apixaban Superior to Warfarin for Preventing Stroke, Reducing Bleeding, and Saving Lives in Patients with Atrial Fibrillation

A large-scale trial finds that apixaban, a new anticoagulant drug, is superior to the standard drug warfarin for preventing stroke and systemic embolism in patients with atrial fibrillation.  Moreover, apixaban results in substantially less bleeding and also results in lower...

Published on 29 August 2011, 04:25


Heart patients could benefit from different drug, study shows

Patients with irregular heart beats could benefit from a drug that is easier to administer than the current standard treatment.The condition, which is more common with older age and affects about 800,000 people in the UK, can lead to blood clots forming and significantly increases the risk of...

Published on 11 August 2011, 04:45


Groundbreaking results in the RE-LY® trial - novel oral direct thrombin inhibitor dabigatran etexilate convincingly beats warfarin - superior stroke reduction with less bleeding!

Compared to well controlled warfarin, dabigatran etexilate showed1: - Significant reduction in the risk of stroke and systemic embolism including hemorrhagic strokes - Significantly lower bleeding including life threatening and intracranial bleeding - Significant reduction in vascular...

Published on 30 August 2009, 05:10


Combination therapy benefits people with quivering heart

Approximately 250,000 Canadians are diagnosed with atrial fibrillation, a condition that causes the upper chambers of the heart to quiver and leads to an increased risk of stroke and complications of circulatory system.Oral blood thinners, such as warfarin and aspirin, are the only proven...

Published on 1 April 2009, 09:44


Right warfarin dose determined by three genes

Researchers at Uppsala University, together with colleagues at the Karolinska Institute and the Sanger Institute, have now found all the genes the determine the dosage of the blood-thinning drug warfarin. The findings are published in the scientific journal PLoS Genetics."We have previously...

Published on 20 March 2009, 12:29


Genome-wide association scan reveals the landscape of inherited variability in response to warfarin dose

Genes determining the optimal dose of therapeutic warfarin have now been identified in a large-scale, genome-wide association scan (GWAS) of this pharmacogenetic trait. Researchers from the Wellcome Trust Sanger Institute, Uppsala University Hospital, and the Karolinska Institute have found...

Published on 20 March 2009, 02:49


Patients' genetic profiles could prevent fatal doses of common drug

BY KRISTA CONGER       View larger. Russ Altman, MD, PhD, and Teri Klein discuss their findings and the implications for patients who are treated with warfarin...

Published on 25 February 2009, 02:11


Scientists study genes to improve warfarin treatment

Liverpool, UK - 20 February 2009: Scientists at the University of Liverpool have found that information about a patient's genes could help increase the effectiveness of drugs such as warfarin. A team of international researchers, which included scientists from Liverpool and...

Published on 20 February 2009, 18:30


Adding genetics to a patient's clinical profile might lead to more accurate blood-thinner dosing

Including genetic information in a patient's clinical profile might help determine the optimal starting dose of the common blood-thinner warfarin, according to findings from a large-scale study that will be published tomorrow, Thursday, February 19, in the New England Journal of...

Published on 18 February 2009, 16:47


UAB Study Says Kidney Disease Affects Dosage of Blood Thinner Warfarin

BIRMINGHAM, Ala. -- UAB (University of Alabama at Birmingham) researchers say patients with reduced kidney function and kidney failure require lower doses of warfarin, a popular blood thinning medication. These patients also may need closer monitoring to avoid serious bleeding complications,...

Published on 18 February 2009, 16:09


Proper Warfarin Dose Affected by Genetics

• Warfarin dose related to two genes• Personalized medicine precursor: dose adjusted to patient's genetic makeup• UAB part of International Warfarin Pharmacogenetics ConsortiumBIRMINGHAM, Ala. - An individual's genetic makeup can have a profound effect on the required...

Published on 18 February 2009, 16:04


Boston University School Of Medicine Study Shows Optimal Dose Management Of Warfarin Improves Antico

(Boston)- Researchers from Boston University School of Medicine (BUSM) have determined the optimal dose-management strategy to derive maximal benefit from warfarin therapy and improve patient outcomes. Results of the study appear online in the December 2008 issue of the Journal of Thrombosis and...

Published on 22 December 2008, 09:58


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