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Sepsis News (21 articles)



IU researchers uncover protein's job protecting pneumonia-causing pathogen from copper poisoning

BLOOMINGTON, Ind. -- A team of chemists and biologists led by Indiana University chemistry professor David Giedroc has described a previously unknown function of a protein they now know is responsible for protecting a major bacterial pathogen from toxic levels of copper. The results were...

Published on 28 January 2013, 08:37


Cholesterol-Lowering Statins Boost Bacteria-Killing Cells

Widely prescribed for their cholesterol-lowering properties, recent clinical research indicates that statins can produce a second, significant health benefit: lowering the risk of severe bacterial infections such as pneumonia and sepsis. A new explanation for these findings has been...

Published on 17 November 2010, 12:40


Action of Modern Drug Demonstrates How Two Ancient Human Systems Interact, Penn Study Finds

Implications for Reducing Clotting in Kidney Disease Dialysis and Sepsis.PHILADELPHIA –The interaction of the drug compstatin with two ancient, co-evolved human systems points to new ways for reducing clotting during dialysis for end-stage kidney disease and multiple organ failure due to...

Published on 16 June 2010, 14:50


Researchers Make Blood Poisoning Breakthrough

The lives of millions of people struck down by blood poisoning – or sepsis – could be saved after a team of researchers, including an expert from the University of Glasgow, made a medical breakthrough in how the condition is treated.Blood poisoning often develops into septic shock which is an...

Published on 4 June 2010, 05:51


Breakthrough in Treatment for Sepsis

University scientists have made an important breakthrough in the potential treatment of blood poisoning or Sepsis.The finding, reported online (13 May 2010) in the scientific journal Nature Medicine, could see new therapies being developed in order to more effectively treat the potentially lethal...

Published on 17 May 2010, 10:01


Leptin Action in the Brain Linked to Sepsis Survival

CINCINNATI—The hormone leptin, typically associated with body weight regulation, works within the central nervous system (CNS) to aid the immune system’s defense against sepsis, researchers say. Sepsis is a life-threatening medical condition in which the entire body is overwhelmed by...

Published on 30 April 2010, 13:49


Novartis receives approval in the European Union for Menveo®, first quadrivalent conjugate vaccine in the EU to help prevent meningococcal disease

. Meningococcal disease is a major cause of bacterial meningitis and sepsis with high consequent disability and mortality rates worldwide[1]. Dominant groups of meningococcal disease vary by country and region, and can change over time, making it an even more unpredictable disease[2]. Menveo...

Published on 18 March 2010, 04:57


Novartis meningococcal vaccine Menveo® recommended for approval in the European Union for prevention of disease in adolescents and adults

. Investigational vaccine Menveo demonstrates a protective immune response in four of the five major bacteria groups responsible for meningococcal disease . Meningococcal disease is a major cause of bacterial meningitis and sepsis with high consequent disability and mortality rates...

Published on 18 December 2009, 08:51


Histone Molecules Found to Drive Organ Failure During Sepsis

When the immune system responds to an infection by going into overdrive, small blood clots can form, blocking blood flow to vital organs. The condition, called sepsis, kills about 215,000 people in the United States annually. New research shows that histones — the protein spools that help keep...

Published on 25 October 2009, 14:11


Canadian scientists link fat hormone to death from potentially deadly blood infection

Adiponectin found in body fat may hold the key to preventing and treating sepsisA new Canadian study has found that lower-than-normal levels of a naturally-occurring fat hormone may increase the risk of death from sepsis—an overwhelming infection of the blood which claims thousands of lives...

Published on 23 October 2009, 20:11


Leading Pathogen in Newborns Can Suppress Immune Cell Function

Group B Streptococcus (GBS), a bacterial pathogen that causes sepsis and meningitis in newborn infants, is able to shut down immune cell function in order to promote its own survival, according to researchers at the University of California, San Diego School of Medicine and the Skaggs School of...

Published on 13 July 2009, 14:42


Discovery of Key Protein that Regulates Inflammation Spells New Hope for ICU Patients

Sepsis – the leading cause of death in non-coronary ICU patients – may now be brought under control  1. Sepsis, the severe inflammatory condition caused by bacterial infection, which commonly afflicts patients in intensive care units (ICU), may soon be less...

Published on 14 May 2009, 05:13


Packard/Stanford study suggests two causes for bowel disease in infants

STANFORD, Calif. — New research from Lucile Packard Children’s Hospital and the Stanford University School of Medicine is helping physicians unravel the cause of a deadly and mysterious bowel disease that strikes medically fragile newborn babies. The findings could lead to a better...

Published on 27 April 2009, 10:47


A fast magnetic fix for sepsis?

Micromagnetic-microfluidic device could quickly pull pathogens from the bloodstrea. Sepsis, an infection of the blood, can quickly overwhelm the body's defenses and is responsible for more than 200,000 deaths per year in the U.S. alone. Premature newborns and people with weakened...

Published on 25 March 2009, 15:32


Micromagnetic-microfluidic device could quickly pull pathogens from the bloodstream

Sepsis, an infection of the blood, can quickly overwhelm the body's defenses and is responsible for more than 200,000 deaths per year in the U.S. alone. Premature newborns and people with weakened immune systems are especially vulnerable. Since most existing treatments are ineffective,...

Published on 23 March 2009, 16:24


Life-and-death protein regulates immune system’s “emergency team”

 White blood cells called neutrophils and macrophages are the first responders of the immune system. They serve as the first line of defense against invading microbes—identifying them, engulfing them and eliminating them. However, once these protective cells have obliterated their...

Published on 12 March 2009, 02:55


Children's National Research Links Platelets to Sepsis-Related Organ Failure

Conventionally thought to be the bloodstream’s “innocent bystanders,” platelets may actually play a more sinister role in organ failure caused by severe sepsis -WASHINGTON, DC—Scientists at Children’s National Medical Center have identified a previously unknown...

Published on 10 March 2009, 11:18


Researchers probe mechanisms of infection

DALLAS — March 9, 2009 — A newly discovered receptor in a strain of Escherichia coli might help explain why people often get sicker when they’re stressed.Researchers at UT Southwestern Medical Center are the first to identify the receptor, known as QseE, which resides in a...

Published on 9 March 2009, 17:45


No 'Death NET?' That May Explain Why Millions of Infants Are at Risk for Potentially Deadly Blood Infection

U of U researchers identify critical difference in white blood cells of preterm babiesSALT LAKE CITY - When locked in mortal combat with infection, some mature white blood cells have a formidable weapon: they literally cast a DNA net-called a neutrophil extracellular trap (NET)-that captures and...

Published on 9 March 2009, 13:24


Researchers Block Immune Cell Rush Behind Deadly Sepsis

Mortality from Blood Poisoning on the Rise  Researchers have found a way to block the ability of white blood cells to sprint toward the sites of infection when such speed worsens the damage done by sepsis, the often fatal,...

Published on 24 February 2009, 13:56


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