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RNAi News (6 articles)

Researchers achieve RNA interference, in a lighter package

Pared-down nucleic acid nanoparticle poses less risk of side effects, offers better targeting.Cambridge, MASS. -- Using a technique known as “nucleic acid origami,” chemical engineers have built tiny particles made out of DNA and RNA that can deliver snippets of RNA directly to tumors,...

Published on 4 June 2012, 10:36

Penn Study Describes First Proof of Principle for Treating Rare Bone Disease

PHILADELPHIA - Scientists at Penn’s Perelman School of Medicine Center for Research in FOP and Related Disorders have developed a new genetic approach to specifically block the damaged copy of the gene for a rare bone disease, while leaving the normal copy untouched.Lead author Josef...

Published on 4 November 2011, 10:53

Suggesting genes’ friends, facebook-style: New method reveals genes’ combined effects

Scientists at the European Molecular Biology Laboratory (EMBL) and the German Cancer Research Centre (DKFZ), both in Heidelberg, Germany, have developed a new method that uncovers the combined effects of genes. Published online today in Nature Methods, it helps understand how different genes...

Published on 6 March 2011, 14:03

Researchers find gene-silencing nanoparticles may put end to pesky summer pest

MANHATTAN -- Summer just wouldn't be complete without mosquitoes nipping at exposed skin. Or would it?Research conducted by a Kansas State University team may help solve a problem that scientists and pest controllers have been itching to for years.Kun Yan Zhu, professor of entomology, and...

Published on 19 July 2010, 09:27

Caltech-led Team Provides Proof in Humans of RNA Interference Using Targeted Nanoparticles

Researchers unveil scientific results from siRNA Phase I clinical trial in cancer patients.PASADENA, Calif.—A California Institute of Technology (Caltech)-led team of researchers and clinicians has published the first proof that a targeted nanoparticle—used as an experimental therapeutic and...

Published on 21 March 2010, 13:38

The Future of Personalized Cancer Treatment: An Entirely New Direction for RNAi Delivery

In technology that promises to one day allow drug delivery to be tailored to an individual patient and a particular cancer tumor, researchers at the University of California, San Diego School of Medicine, have developed an efficient system for delivering siRNA into primary cells. The work will be...

Published on 18 May 2009, 11:56