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PXR News (2 articles)

Targeting the Blood-Brain Barrier May Delay Progression of Alzheimer's Disease

Researchers may be one step closer to slowing the onset and progression of Alzheimer's disease. An animal study supported by the National Institute of Environmental Health Sciences (NIEHS), part of the National Institutes of Health, shows that by targeting the blood-brain barrier,...

Published on 12 April 2010, 09:00

Scientists reveal a new mechanism that increases atherosclerosis in mice

A shot of espresso may rev you up in the morning, but the downside is that it may also ramp up levels of bad cholesterol due to its effects on a unique liver protein called PXR. New research from Rockefeller University now shows that when chronically activated, the protein rejiggers how...

Published on 4 November 2009, 15:55