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Macrophages News (20 articles)



Dousing The Flames: New studies suggest that certain microRNAs play a role in the development of arteriosclerosis.

New studies suggest that certain microRNAs play a role in the development of arteriosclerosis. Inhibition of a specific microRNA has been shown to suppress inflammatory reactions in an animal model, and it may someday help to prevent heart attacks.Arteriosclerosis results from a persistent...

Published on 12 October 2012, 08:19


Mystery to the origin of long-lived, skin-deep immune cells uncovered

Scientists at A*STAR’s Singapore Immunology Network (SIgN) uncovered the origin of a group of skin-deep immune cells that act as the first line of defence against harmful germs and skin infections. SIgN scientists discovered that these sentry cells of the skin, called the Langerhans cells...

Published on 7 June 2012, 05:04


Antidiabetic drug inhibits dangerous inflammation of adipose tissue

The fat tissue around the waist (abdominal fat) of obese persons is chronically inflamed – this is regarded as one of the major causes for the development of type 2 diabetes. In mice with normal body weight, a specific group of immune cells keeps these inflammations in check. Scientists of...

Published on 21 May 2012, 15:35


Scientists pinpoint how vitamin D may help clear amyloid plaques found in Alzheimer's

A team of academic researchers has identified the intracellular mechanisms regulated by vitamin D3 that may help the body clear the brain of amyloid beta, the main component of plaques associated with Alzheimer's disease.Published in the March 6 issue of the Journal of Alzheimer's...

Published on 6 March 2012, 15:25


Heavy Metals Boost Immunity

A new natural defense mechanism against infections has been evidenced by an international team led by researchers from CNRS, Inserm, the Institut Pasteur and the Université Paul Sabatier – Toulouse III(1). Zinc, a heavy metal that is toxic at high doses, is used by the cells of the immune...

Published on 21 September 2011, 06:08


New Treatment Can Destroy Prostate Cancer From Within

A 'Trojan horse' system developed by researchers at the Universities of Sheffield and York attacks cancerous cells from within and potentially offers a safer treatment for prostate tumours.The technique involves the use of a patient´s own white blood cells called macrophages to...

Published on 12 April 2011, 06:35


Scientists find the “master switch” for key immune cells in inflammatory diseases

Scientists have identified a protein that acts as a “master switch” in certain white blood cells, determining whether they promote or inhibit inflammation. The study, published in the journal Nature Immunology, could help researchers look for new treatments for diseases such as rheumatoid...

Published on 17 January 2011, 05:56


Macrophage Protein Has Major Role in Inflammation

Researchers at the University of California, San Diego School of Medicine have discovered that a multi-tasking protein called FoxO1 has another important but previously unknown function: It directly interacts with macrophages, promoting an inflammatory response that can lead to insulin...

Published on 2 November 2010, 13:13


Why Fish Oils Work Swimmingly Against Diabetes

Researchers at the University of California, San Diego School of Medicine have identified the molecular mechanism that makes omega-3 fatty acids so effective in reducing chronic inflammation and insulin resistance.The discovery could lead to development of a simple dietary remedy for many of...

Published on 2 September 2010, 15:07


A Breakthrough in Tuberculosis Research

Often causing no symptoms in carriers of the disease, worldwide tuberculosis (TB) infects eight to ten million people every year, kills two million, and it is highly contagious as it is spread through coughing and sneezing. “It’s a global health disaster waiting to happen, even here in...

Published on 29 July 2010, 15:21


Low Oxygen Recruits Inflammatory Cells to Tumors, Stimulating Growth, Penn Researchers Find

WASHINGTON, DC - The inner regions of tumors have a low-oxygen content and often contain inflammatory cells called macrophages, which researchers suspect promote tumor growth. Now, University of Pennsylvania School of Medicine researchers show that this is the case: Tumor cells in this...

Published on 21 April 2010, 11:18


Damaging Inflammatory Response Could Hinder Spinal Cord Repair

COLUMBUS, Ohio – The inflammatory response following a spinal cord injury appears to be set up to cause extra tissue damage instead of promoting healing, new research suggests.Scientists analyzing this inflammatory response in mice discovered that the types of cells recruited to the site of the...

Published on 21 October 2009, 16:03


Study identifies cellular mechanism that causes lupuslike symptoms in mice

Macrophages, the scavenger cells of the body’s immune system, are responsible for disposing of dying cells. Stanford University School of Medicine researchers have identified one pathway in this important process in mice that, if disrupted, causes a lupuslike autoimmune disease.The findings...

Published on 18 October 2009, 15:25


Major discovery opens door to leishmania treatment

Researchers at MUHC/McGill uncover key role played by a molecule in the process of infection used by the parasite that causes leishmania.Leishmania is a deadly parasitic disease that affects over 12 million people worldwide, with more than 2 million new cases reported every year. Until recently,...

Published on 6 October 2009, 12:55


Researchers image crucial anthrax protein

Crystal structure could offer new therapies.ARGONNE, Ill. (July 14, 2009) — Anthrax, long feared for its potential as a biological weapon, has lost some of its mystery. Researchers at the U.S. Department of Energy's (DOE) Argonne National Laboratory, in collaboration with scientists at...

Published on 14 July 2009, 10:43


Sequentially and Structurally Unique Portion of Emphysema-related Enzyme Directly Fights Bacterial Lung Infection

Pitt Researchers Report in Nature that Sequentially and Structurally Unique Portion of Emphysema-related Enzyme Directly Fights Bacterial Lung Infection. PITTSBURGH– An enzyme known to play a key role in the development of emphysema serves as the first line of defense against bacterial...

Published on 18 June 2009, 03:58


How germs meet their opposites - a mystery revealed in real time

Sophisticated microscope technology has made it possible for Australian and American scientists to record previously unknown interactions between two classes of immune cell right at the beginning of the 'antigen transport chain', the apex of the immune response.Using intravital...

Published on 9 June 2009, 04:32


Research suggests new cellular targets for HIV drug development

GAINESVILLE, Fla. — Focusing HIV drug development on immune cells called macrophages instead of traditionally targeted T cells could bring us closer to eradicating the disease, according to new research from University of Florida and five other institutions.In the largest study of its kind,...

Published on 27 May 2009, 12:02


New Light Shed on the Enigma of Salt Intake and Hypertension

A high salt intake has been implicated in cardiovascular disease risk for 5000 years. But salt-sensitive hypertension still remains an enigma. Now, investigators from Germany at the University of Erlangen, the Max Delbrück Center for Molecular Medicine (MDC) Berlin-Buch and Regensburg,...

Published on 4 May 2009, 09:19


New study overturns orthodoxy on how macrophages kill bacteria

CHAMPAIGN, Ill. — For decades, microbiologists assumed that macrophages, immune cells that can engulf and poison bacteria and other pathogens, killed microbes by damaging their DNA. A new study from the University of Illinois disproves that.The study, published in the journal PLoS One,...

Published on 27 April 2009, 12:19


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