Macrophages News (12 articles)

Researchers at the University of California, San Diego School of Medicine have identified the molecular mechanism that makes omega-3 fatty acids so effective in reducing chronic inflammation and insulin resistance.The discovery could lead to development of a simple dietary remedy for many of...

Published on 2 September 2010, 15:07

Categories: Diabetes GPR120 receptor Insulin resistance Macrophages Omega 3 fatty acids Omega-3

Often causing no symptoms in carriers of the disease, worldwide tuberculosis (TB) infects eight to ten million people every year, kills two million, and it is highly contagious as it is spread through coughing and sneezing. “It’s a global health disaster waiting to happen, even here in...

Published on 29 July 2010, 15:21

Categories: Apoptosis Eicosanoids Immune System Macrophages TB Tuberculosis

WASHINGTON, DC - The inner regions of tumors have a low-oxygen content and often contain inflammatory cells called macrophages, which researchers suspect promote tumor growth. Now, University of Pennsylvania School of Medicine researchers show that this is the case: Tumor cells in this...

Published on 21 April 2010, 11:18

Categories: Macrophages Tumor growth Oxygen Hypoxia Cancer

COLUMBUS, Ohio – The inflammatory response following a spinal cord injury appears to be set up to cause extra tissue damage instead of promoting healing, new research suggests.Scientists analyzing this inflammatory response in mice discovered that the types of cells recruited to the site of the...

Published on 21 October 2009, 16:03

Categories: Inflammation M1 macrophages M2 macrophages Macrophages Spinal Cord Spinal cord injury

Macrophages, the scavenger cells of the body’s immune system, are responsible for disposing of dying cells. Stanford University School of Medicine researchers have identified one pathway in this important process in mice that, if disrupted, causes a lupuslike autoimmune disease.The findings...

Published on 18 October 2009, 15:25

Categories: Autoimmune diseases Autoimmunity Lupus lupuslike symptoms Macrophages PPAR-delta

Researchers at MUHC/McGill uncover key role played by a molecule in the process of infection used by the parasite that causes leishmania.Leishmania is a deadly parasitic disease that affects over 12 million people worldwide, with more than 2 million new cases reported every year. Until recently,...

Published on 6 October 2009, 12:55

Categories: GP63 Leishmania Macrophages Molecular Biology Parasites

Crystal structure could offer new therapies.ARGONNE, Ill. (July 14, 2009) — Anthrax, long feared for its potential as a biological weapon, has lost some of its mystery. Researchers at the U.S. Department of Energy's (DOE) Argonne National Laboratory, in collaboration with scientists at...

Published on 14 July 2009, 10:43

Categories: Anthrax Anthrax bacterium Bacteria Biochemistry CapD Macrophages PDGA

Pitt Researchers Report in Nature that Sequentially and Structurally Unique Portion of Emphysema-related Enzyme Directly Fights Bacterial Lung Infection. PITTSBURGH– An enzyme known to play a key role in the development of emphysema serves as the first line of defense against bacterial...

Published on 18 June 2009, 03:58

Categories: Bacteria Emphysema Enzymes Lungs Macrophages Matrix metalloproteinase-12 MMP-12

Sophisticated microscope technology has made it possible for Australian and American scientists to record previously unknown interactions between two classes of immune cell right at the beginning of the 'antigen transport chain', the apex of the immune response.Using intravital...

Published on 9 June 2009, 04:32

Categories: antigen transport chain' B cells Immunology Lymph Macrophages Microscope technology SCS macrophages

GAINESVILLE, Fla. — Focusing HIV drug development on immune cells called macrophages instead of traditionally targeted T cells could bring us closer to eradicating the disease, according to new research from University of Florida and five other institutions.In the largest study of its kind,...

Published on 27 May 2009, 12:02

Categories: HIV Macrophages T Cells HIV drug development Immunology

A high salt intake has been implicated in cardiovascular disease risk for 5000 years. But salt-sensitive hypertension still remains an enigma. Now, investigators from Germany at the University of Erlangen, the Max Delbrück Center for Molecular Medicine (MDC) Berlin-Buch and Regensburg,...

Published on 4 May 2009, 09:19

Categories: Hypertension Macrophages NaCl Natrium Chloride Salt Skin TonEBP

CHAMPAIGN, Ill. — For decades, microbiologists assumed that macrophages, immune cells that can engulf and poison bacteria and other pathogens, killed microbes by damaging their DNA. A new study from the University of Illinois disproves that.The study, published in the journal PLoS One,...

Published on 27 April 2009, 12:19

Categories: Bacteria DNA Macrophages Microbiology Reactive Oxygen Species ROS