Liver News (19 articles)

CAMBRIDGE, Mass. — Researchers at MIT and Alnylam Pharmaceuticals report this week that they have successfully used RNA interference to turn off multiple genes in the livers of mice, an advance that could lead to new treatments for diseases of the liver and other organs.Since the 1998 discovery...

Published on 29 December 2009, 08:16

Categories: Bioengineering C12-200 Gene Silencing Lipidoids Liver RNA RNA interference siRNA

A team of scientists from the UC San Diego School of Medicine and Osaka University in Japan have identified a protein switch that helps prevent liver damage, including inflammation, fibrosis and cancer. The findings suggest that a better understanding of how the protein, TAK1, works could lead to...

Published on 14 December 2009, 15:01

Categories: JNK Kinase Liver Liver Cancer Liver Diseases NF-kappaB Proteins TAK1

A well-known Eastern medicine supplement may help avoid the most common cause of liver transplantation, according to a study by researchers at the Stanford University School of Medicine. The finding came as a surprise to the scientists, who used a number of advanced genetic and genomic techniques...

Published on 18 November 2009, 04:42

Categories: Acetaminophen Bhmt2 Glutathione Herbal medicine LIver Liver Failure Pain reliever S-methylmethionine SMM Toxicity Vitamin U

(Boston) - Researchers from Boston University School of Medicine (BUSM) have shown that fat collection in different body locations, such as around the heart and the aorta and within the liver, are associated with certain decreased heart functions. The study, which appears on-line in Obesity, also...

Published on 13 November 2009, 09:03

Categories: Medicine Obesity BMI Heart Aorta Liver

A combination of bioengineering and medical research at the University of California, San Diego has led to a new discovery that could pave the way for more effective treatments for liver disease.In this work, the researchers have utilized an array system that can identify the biological...

Published on 12 October 2009, 17:16

Categories: Bioengineering Liver diseases Liver Hepatic stellate cells HSCs

BBSRC-funded scientists have discovered a previously unknown link between a mother’s diet in pregnancy and a severe form of liver disease in her child.In a study, published in the journal Hepatology today, researchers at the University of Southampton found that a high fat diet during a...

Published on 9 October 2009, 07:02

Categories: Fat High fat diet Liver Liver diseases NAFLD Non-alcoholic fatty liver disease Pregnancy

Research by UC Riverside scientists is first to link passive smoking to nonalcoholic fatty liver disease.RIVERSIDE, Calif. – A team of scientists at the University of California, Riverside has found that even second-hand tobacco smoke exposure can result in nonalcoholic fatty liver disease...

Published on 10 September 2009, 16:28

Categories: Liver Liver Diseases NAFLD Nonalcoholic fatty liver disease Passive smoking Second-Hand Smoking SREBP

GAINESVILLE, Fla. — University of Florida researchers have safely given new, functional genes to patients with a hereditary defect that can lead to fatal lung and liver diseases, according to clinical trial findings slated to appear this week in the online early edition of the Proceedings...

Published on 11 August 2009, 04:23

Categories: Alpha-1 Alpha-1 antitrypsin Diseases hereditary defect Liver Lung Proteins

Case Studies: Dietary Supplements with Steroids Pose Health Danger.DETROIT - Three cases of patients suffering from the adverse affects of steroid-enriched dietary supplements have been reported by researchers at Henry Ford Hospital.The cases, which include patients with liver injury and renal...

Published on 5 August 2009, 04:13

Categories: Dietary Supplements Steroids Anabolic steroids Liver

Findings Point to Clues for Regenerative Therapies. PHILADELPHIA - Understanding the molecular signals that guide early cells in the embryo to develop into different organs provides insight into ways that tissues regenerate and how stem cells can be used for new therapies. With regenerated...

Published on 26 June 2009, 09:09

Categories: Cell Biology Embryo Genes Liver Pancreas Stem Cells

New Haven, Conn. — In research that could lead to new approaches for the treatment of type 2 diabetes, a Yale School of Medicine team has found that suppressing a liver enzyme that induces glucose production helped diminish the symptoms of the disease in a rat model — reducing blood...

Published on 17 June 2009, 13:47

Categories: Cholesterol Glucose Insulin sensitivity Liver Sirtuin 1 Type 2 Diabetes

ROCHESTER, Minn. — Researchers have discovered a novel molecular path that predisposes patients to develop primary biliary cirrhosis, a disease that mainly affects women and slowly destroys their livers. Primary biliary cirrhosis has no known cause.The finding, significant because it is a...

Published on 27 May 2009, 16:02

Categories: Primary Biliary Cirrhosis Liver Diseases

Scientists in Sydney and Boston believe they may have identified a gene that controls abnormal production of sugar in the liver, a very troublesome problem for people with diabetes.The liver is the sugar factory for the body - when blood sugar (glucose) levels fall, the liver makes and releases...

Published on 19 May 2009, 03:42

Categories: ARNT Glucose Liver Sugar Type 2 diabetes

UC San Diego study says relatives of children with NAFLD considered ‘high risk’Family members of children diagnosed with non-alcoholic fatty liver disease (NAFLD) should be considered at high risk for the disease and tested for it as part of a routine medical examination, even if they...

Published on 2 May 2009, 12:48

Categories: Liver NAFLD Non-Alcoholic Fatty Liver Disease

UCL Business and biopharmaceutical company Ocera Therapeutics Inc have signed an exclusive worldwide licensing agreement for UCL-L1V – a compound that can be used to treat acute hepatic encephalopathy (AHE) based on international research led by Professor Rajiv Jalan and the Liver Failure...

Published on 2 April 2009, 06:55

Categories: UCL-L1V Acute Hepatic Encephalopathy AHE Hepatology Liver

AMES, Iowa -- Research by an Iowa State University scientist suggests that cholesterol-reducing drugs known as statins may lessen brain function.Yeon-Kyun Shin, a biophysics professor in the department of biochemistry, biophysics and molecular biology, says the results of his study show that...

Published on 23 February 2009, 17:19

Categories: Biochemistry Brain Brain functions Cholesterol HDL LDL Liver Statins

In a world first, a UQ researcher has developed a non-invasive screening method for potentially fatal liver and intestinal flukes plaguing the lives of an estimated 9 million people throughout southeast Asia. The PCR test is already being used by Thai researchers to screen people for the...

Published on 11 February 2009, 03:01

Categories: Diseases Flukes Liver Medicine PCR test

DALLAS — Feb. 3, 2009 — Researchers at UT Southwestern Medical Center have uncovered crucial clues about a paradoxical disease in which patients with no body fat develop many of the health complications usually found in obese people.The findings in mice, appearing online today in Cell...

Published on 3 February 2009, 13:25

Categories: Fat-free diet Fat Liver Paradoxical diseases AGPAT2 Biochemistry

A novel protein marker has been found that identifies rare adult liver stem cells, whose ability to regenerate injured liver tissue has the potential for cell-replacement therapy. For the first time, researchers at the University of Pennsylvania School of Medicine led by Linda...

Published on 17 November 2008, 16:27

Categories: Liver Diseases Liver Stem cells Gastroenterology