Drug Delivery News (19 articles)

New approach could dramatically improve the success rate of immune-cell therapies.CAMBRIDGE, Mass. — Clinical trials using patients’ own immune cells to target tumors have yielded promising results. However, this approach usually works only if the patients also receive large doses of drugs...

Published on 15 August 2010, 16:33

Categories: Nanoparticles Nanotechnology Drug Delivery Drugs Tumors

Findings hold important implications for cancer therapy.The application of nanotechnology in the field of drug delivery has attracted much attention in recent years. In cancer research, nanotechnology holds great promise for the development of targeted, localized delivery of anticancer drugs,...

Published on 9 July 2010, 08:02

Categories: Nanoparticles Cancer Nanotechnology Drug Delivery Mesoporous silica nanoparticles MSNs Chemotherapeutic drugs

A team led by researchers from North Carolina State University has developed two new approaches for incorporating antimicrobial properties into microneedles – vanishingly thin needles that hold great promise for use in portable medical devices. Researchers expect the findings to spur...

Published on 19 May 2010, 09:48

Categories: Drug Delivery Medical devices Microneedles Two Photon Polymerization

For the first time, scientists have succeeded in growing empty particles derived from a plant virus and have made them carry useful chemicals.The external surface of these nano containers could be decorated with molecules that guide them to where they are needed in the body, before the chemical...

Published on 11 March 2010, 05:32

Categories: Biomaterials Chemicals Cowpea mosaic virus Drug Delivery Drugs Nanotechnology

A team of engineers, chemists, and clinicians lead by Yolonda Colson, MD, PhD of Brigham and Women's Hospital and Mark W. Grinstaff, PhD of Boston University have developed a unique new drug delivery device for the prevention of lung tumor recurrence after surgical resection. Their research...

Published on 3 February 2010, 10:51

Categories: Chemotherapeutic Polymer Films Drug Delivery Lung Cancer Lung Tumor Lungs Oncology Polymer Films

The oral route is the most common and preferred route of drug delivery in view of its convenience and patient acceptance, even more so in the case of chronic therapies. However, many upcoming therapeutic entities are characterized by various problems for oral administration, such as a low degree...

Published on 21 December 2009, 07:34

Categories: Drug Delivery Drug Delivery System drugs Micelles Nanoscience Oral delivery pH pH-sensitive polymer Polymeric Micelles

CAMBRIDGE, Mass. — MIT scientists including Elazer R. Edelman, the Thomas D. and Virginia W. Cabot Professor of Health Science and Technology (HST), and HST postdoctoral associate Vijaya B. Kolachalama, developed computer models to predict physiologically realistic drug delivery patterns from...

Published on 2 December 2009, 04:35

Categories: Computer Models Drug delivery Drug-eluting Stents Stents

Mouse tumors reduced after just one treatment.DURHAM, N.C. -- Going smaller could bring better results, especially when it comes to cancer-fighting drugs.Duke University bioengineers have developed a simple and inexpensive method for loading cancer drug payloads into nano-scale delivery vehicles...

Published on 30 October 2009, 15:11

Categories: Chemotherapy Nanoscience Drug Delivery Tumors Nano-delivery systems

Researchers at the Smurfit Institute of Genetics’ Ocular Genetics Unit at Trinity College Dublin have reported the development of a new drug delivery system which has the potential to treat degenerative diseases of the retina, including retinitis pigmentosa, age-related macular degeneration and...

Published on 13 October 2009, 10:17

Categories: Age-related macular degeneration Diabetic retinopathy Drug Delivery Drug Delivery System Macular degeneration Retina Retinal Diseases Retinitis pigmentosa

Boston, Mass. -- September 18, 2009 -- Many medical conditions, such as chronic pain, cancer and diabetes, require medications that cannot be taken orally, but must be dosed intermittently, on an as-needed basis, over a long period of time. A few delivery techniques have...

Published on 18 September 2009, 16:11

Categories: Drug Delivery Magnetism Nanotechnology

(Santa Barbara, Calif.) –– Researchers at UC Santa Barbara have developed a new way to deliver drugs into cancer cells by exposing them briefly to a non-harmful laser. Their results are published in a recent article in ACS NANO, a journal of the American Chemical Society."This...

Published on 10 September 2009, 05:14

Categories: Drug Delivery Lasers Nanoparticles Nanoscience siRNA

(Santa Barbara, Calif.) –– Scientists at UC Santa Barbara have discovered a potential new drug delivery system. The finding is a biological mechanism for delivery of nanoparticles into tissue. The results are published in this week's Proceedings of the National Academy of...

Published on 24 August 2009, 18:41

Categories: Drug Delivery Drug Delivery System Drugs Nanoscience

WEST LAFAYETTE, Ind. - Sumith Kularatne and Philip Low Download photo caption below A new prostate cancer "homing device" could improve detection and allow for the first targeted treatment of the disease.A team of Purdue University...

Published on 6 July 2009, 16:26

Categories: Biochemistry Drug delivery Prostate Cancer Prostate-specific membrane antigen PSMA

It is now possible to engineer tiny containers the size of a virus to deliver drugs and other materials with almost 100 percent efficiency to targeted cells in the bloodstream.According to a new Cornell study, the technique could one day be used to deliver vaccines, drugs or genetic material to...

Published on 25 June 2009, 16:33

Categories: Drug delivery Bioengeneering Nanotechnology Selectins Bloodstream

Method could yield futuristic devices smaller than cells for "smart delivery" of drugs.By combining the art of origami with nanotechnology, Dana-Farber Cancer Institute researchers have folded sheets of DNA into multilayered objects with dimensions thousands of times smaller than the...

Published on 20 May 2009, 16:11

Categories: Art of origami Biomedical devices DNA origami Drug delivery Nanodevices Nanotechnology Origami

In technology that promises to one day allow drug delivery to be tailored to an individual patient and a particular cancer tumor, researchers at the University of California, San Diego School of Medicine, have developed an efficient system for delivering siRNA into primary cells. The work will be...

Published on 18 May 2009, 11:56

Categories: Biotechnology Cell Biology Drug Delivery Peptide Transduction Domain Proteins PTD RNAi siRNAs

University Park, Pa. -- Specialized motor proteins that transport cargo within cells could be turned into nanoscale machines for drug delivery, according to bioengineers. Chemical alteration of the proteins' function could also help inhibit the growth of cancerous tumors.Each cell in the...

Published on 20 March 2009, 12:18

Categories: Drug delivery Bioengeneering Motor proteins Biochemistry kinesin-2

Self-assembling hydrogel could help treat cancer and diabetes, among other diseasesMIT researchers have demonstrated that a gel composed of small, woven protein fragments can successfully carry and release proteins of different sizes, potentially enabling delivery of drugs such as insulin and...

Published on 9 March 2009, 16:16

Categories: Biomedical Engineering Diseases Drug delivery Gel Nanofiber hydrogel scaffold Proteins

Researchers at North Carolina State University have successfully modified a common plant virus to deliver drugs only to specific cells inside the human body, without affecting surrounding tissue. These tiny "smart bombs" - each one thousands of times smaller than the width of a human...

Published on 12 February 2009, 11:12

Categories: Nanotechnology Chemistry Plant virus Chemotherapy drugs "Smart Bomb" Drug Delivery