Breast Cancer News (153 articles)

'An interesting step along a long path of research,' McGill scientist saysNew research led by McGill Biochemist Dr. William Muller helps explain why breast-milk cells lose their structure, causing them to clump up in strange ways (see photos) and sometimes become cancer tumors. With the...

Published on 30 April 2010, 14:05

Categories: Biochemistry Breast Cancer Breast Milk Breast-tumour Growth Genes Proteins

Washington, DC --An increase in breast density appears to be the culprit behind an increase of breast cancer found in women participating in the estrogen and progestin therapy study, a part of the Women’s Health Initiative (WHI). That is the finding of a new WHI analysis led by Celia Byrne,...

Published on 21 April 2010, 11:30

Categories: Breast Density Cancer Breast Cancer EPT Estrogen plus progestin therapy Estrogen Progestin Hormones Hormone replacement therapy

WASHINGTON — A decrease in breast density, or the proportion of fibroglandular tissue depicted on the mammogram image, over a number of years is associated with decreased risk of breast cancer, researchers from the Mayo Clinic campus in Minnesota report at the American Association for Cancer...

Published on 20 April 2010, 16:04

Categories: Breast Cancer Breast Density Breast Fibroglandular tissue

Washington, DC – A high level of one type of estrogen in a man’s body might increase his risk of developing prostate cancer. That is one surprising conclusion from a new study which also offers another novel finding – that high levels of the estrogen considered fuel for breast cancer might...

Published on 20 April 2010, 08:21

Categories: Estrogen Estrogen Level Prostate Cancer Estrogen metabolites Breast Cancer

Washington, DC – Eating too much fat in pregnancy may be an indulgence that has a less-than-beneficial effect on generations to come, say researchers at Georgetown Lombardi Comprehensive Cancer Center. Their unique study in rats shows that pregnant females that ate a high fat diet not only...

Published on 20 April 2010, 08:08

Categories: Fat Pregnancy High fat diet Breast Cancer Estrogen

SEATTLE — Women with breast cancer before age 55 who carry an inherited mutation in the breast cancer susceptibility genes BRCA1 or BRCA2 are four times more likely to develop cancer in the breast opposite, or contralateral, to their initial tumor as compared to breast cancer patients without...

Published on 6 April 2010, 04:57

Categories: BRCA gene BRCA1 BRCA2 Breast Cancer Cancer Gene Mutation

In a new study in mice, scientists have compensated for mutations in the Brca1 gene that can lead to cancer by deleting a second gene, which then lessens the probability of cancer. Mice Brca1-associated mammary tumors have significant similarities to human BRCA1- associated (BReast CAncer 1,...

Published on 1 April 2010, 11:37

Categories: Brca1 Cancer Genes Breast Cancer 53BP1 Homologous Recombination HR Replication-associated chromosome breaks Gene Mutation

Expression of inflammatory-related genes in breast tissue of women who have previously given birth may explain the aggressiveness and frequency of pregnancy-associated breast cancer, according to new research at the University of Illinois at Chicago. Pregnancy at a relatively young age reduces...

Published on 29 March 2010, 14:37

Categories: Breast Cancer Pregnancy Pregnancy-Associated Breast Cancer

Scientists have found a way to identify which breast cancer patients are likely to respond to a type of chemotherapy.The new test will also predict who is unlikely to see any benefit from the treatment and help to save them from unnecessary side effects.The findings - presented by researchers at...

Published on 26 March 2010, 14:40

Categories: Anthracyclines Breast Cancer Cancer Therapy CEP17 Chemotherapy Chromosome 17 DNA replication Gene Test

Scientists in the Duke Institute for Genome Sciences & Policy (IGSP) say patterns of gene expression in biological pathways activated in the development of breast cancer reveal many new subtypes of the disease. The findings, appearing online in the Proceedings of the National Academy of...

Published on 23 March 2010, 14:19

Categories: Breast Cancer Gene expression Breast cancer subtypes

BLOOMINGTON, Ind. -- Women's responsiveness to the second-line breast cancer drug fulvestrant may depend on whether the cancer cells are expressing two key proteins, Indiana University Bloomington scientists report in this month's Cancer Biology & Therapy.Fulvestrant appeared to...

Published on 10 March 2010, 08:11

Categories: Breast Cancer Breast Cancer Drugs Fulvestrant CK8 CK18 Estrogen ER-alpha

Cryoablation generates immune response that kills metastases in mice.Clinical trial open now to evaluate this technique in patients.ANN ARBOR, Mich. — Freezing a cancer kills it in its place, and also appears to generate an immune response that helps stop the cancer’s spread, leading to...

Published on 3 March 2010, 12:41

Categories: Cryoablation Breast Cancer Freezing technique Oncology

Older women who have had breast cancer surgery have a greater risk of the cancer returning if they delay their post-surgical radiation treatment, report Dana-Farber Cancer Institute scientists.The study, which involved more than 18,000 women age 65 and older who had breast cancer, found that...

Published on 3 March 2010, 12:28

Categories: Breast Cancer Breast Cancer Surgery Oncology Radiation

SEATTLE — Women who take some types of bone-building drugs used to prevent and treat osteoporosis may be at lower risk of breast cancer, according to a study by U.S. researchers published today in the British Journal of Cancer.The study found that women who used bisphosphonate drugs, such...

Published on 3 March 2010, 06:52

Categories: Bisphosphonate drugs Bisphosphonates Bones Boniva Breast Cancer Fosamax Osteoporosis Osteoporosis Drugs Zomita

A newly identified cancer biomarker could define a new subtype of breast cancer as well as offer a potential way to treat it, say researchers at Washington University School of Medicine in St. Louis. Their findings published in the March 1 online early edition issue of the Proceedings of the...

Published on 2 March 2010, 07:59

Categories: Breast Cancer LRP6 Biomarkers HER2 PR ER-negative Mesd Low-density lipoprotein receptor-related protein 6

BUFFALO, N.Y. -- Hypnosis can help alleviate the pain and suffering experienced by women being treated for breast cancer, according to a study by a University at Buffalo School of Social Work professor.The randomized trial measured pain and suffering, frequency of pain and degree of constant pain...

Published on 24 February 2010, 14:01

Categories: Hypnosis Pain Breast Cancer Psychotherapy Metastatic Breast Cancer

Chemical found in feverfew, long a staple of natural herbal medicine, shuts down pro-survival signal in resistant breast cancer cells. Washington, DC – Combining tamoxifen, the world’s most prescribed breast cancer agent, with a compound found in the flowering plant feverfew may prevent...

Published on 16 February 2010, 08:20

Categories: Bcl2 Breast Cancer Chemicals Feverfew Herbal medicine Plants Tamoxifen Tamoxifen resistance

New Haven, Conn. — A Yale University-led team of researchers has demonstrated for the first time that variants in a gene responsible for regulating the body’s circadian rhythm may lead to breast cancer. The study appears as an OnlineFirst publication of the journal Cancer Research.Previous...

Published on 3 February 2010, 13:05

Categories: Circadian Rhythm Breast Cancer Epigenetics CLOCK gene

(Boston) - Researchers from the Boston University School of Medicine (BUSM) have determined how the TGFβ-Smad signaling pathway, which is over activated in late-stage cancers, is responsible for the “epigenetic memory” that maintains unique patterns of regulatory DNA hypermethylation causing...

Published on 25 January 2010, 08:37

Categories: Epigenetics TGFβ Cancer DNA hypermethylation Breast Cancer

BOSTON (January 19, 2010) — A study by researchers at Tufts University School of Medicine, the Sackler School of Graduate Biomedical Sciences at Tufts, and Tufts Medical Center improves our current understanding of the origins of breast cancer. The researchers propose a new model for breast...

Published on 19 January 2010, 14:27

Categories: Breast Cancer Breast Stem cells Cancer cyclin D1 Hormones MMTV-ErbB2 Tumorigenesis Progenitor Cells