Breast Cancer News (116 articles)

New Haven, Conn. — A Yale University-led team of researchers has demonstrated for the first time that variants in a gene responsible for regulating the body’s circadian rhythm may lead to breast cancer. The study appears as an OnlineFirst publication of the journal Cancer Research.Previous...

Published on 3 February 2010, 13:05

Categories: Breast Cancer Circadian Rhythm CLOCK gene Epigenetics

(Boston) - Researchers from the Boston University School of Medicine (BUSM) have determined how the TGFβ-Smad signaling pathway, which is over activated in late-stage cancers, is responsible for the “epigenetic memory” that maintains unique patterns of regulatory DNA hypermethylation causing...

Published on 25 January 2010, 08:37

Categories: Breast Cancer Cancer DNA hypermethylation Epigenetics TGFβ

BOSTON (January 19, 2010) — A study by researchers at Tufts University School of Medicine, the Sackler School of Graduate Biomedical Sciences at Tufts, and Tufts Medical Center improves our current understanding of the origins of breast cancer. The researchers propose a new model for breast...

Published on 19 January 2010, 14:27

Categories: Breast Cancer Breast Stem cells Cancer cyclin D1 Hormones MMTV-ErbB2 Tumorigenesis Progenitor Cells

DETROIT - Not only is acupuncture as effective as drug therapy at reducing hot flashes in breast cancer patients, it has the added benefit of potentially increasing a woman's sex drive and improving her sense of well-being, according to a Henry Ford Hospital study.Study results show that...

Published on 1 January 2010, 05:38

Categories: Acupuncture Breast Cancer Hormone Therapy Hot Flashes

A new antibody-drug compound shrank or halted the growth of metastatic breast tumors in almost half of a group of patients whose HER2-positive cancer had become resistant to standard therapies, according to early data from a multicenter Phase II clinical trial led by a Dana-Farber Cancer...

Published on 14 December 2009, 12:03

Categories: Antibodies Breast Cancer DM1 HER2 T-DM1 Trastuzumab Tumors

In an era of minimalist therapy, some mucinous carcinoma patients may need more, not less, treatment.In a large review of breast cancer patients with mucinous carcinoma, researchers at The University of Texas M. D. Anderson Cancer Center have identified an association between this rare type of...

Published on 14 December 2009, 09:01

Categories: Breast Cancer Colloid Carcinoma Mucinous breast cancer Mucinous Carcinoma

Herceptin long-term survival benefits and favourable safety profile confirmed by two pivotal studies.Today, Roche (SIX: RO, ROG; OTCQX: RHHBY) announced new long-term follow up-data from two large pivotal studies evaluating adjuvant Herceptin in HER2-positive early- stage breast cancer presented...

Published on 12 December 2009, 13:10

Categories: HER2-positive HER2 Breast Cancer Herceptin Cancer HER2-positive breast cancer

London UK, Philadelphia, PA – In a clinical study, women with an aggressive form of breast cancer experienced a median survival of 14 months when treated with an investigational combination of TYKERB® (lapatinib) plus HERCEPTIN® (trastuzumab). The results of the Phase III study in...

Published on 11 December 2009, 13:23

Categories: Breast Cancer ErbB2 ErbB2-positive disease HERCEPTIN Lapatinib Trastuzumab TYKERB

HOUSTON -- (December 11, 2009) -- In animal and patient studies, an experimental drug eliminated chemotherapy-resistant breast cancer stem cells – the cells that remain after treatment that could potentially refuel tumor growth, said researchers from Baylor College of Medicine and The...

Published on 11 December 2009, 09:29

Categories: Breast Cancer Breast cancer stem cells Chemotherapy Notch pathway Stem Cells Tumors

Roche to present new results that could offer a better future to women with early and very advanced breast cancer, at the CTRC-AACR San Antonio Breast Cancer Symposium.Roche (SIX: RO, ROG; OTCQX: RHHBY) announced today that new 5 year follow-up data from two pivotal studies with Herceptin®...

Published on 9 December 2009, 04:44

Categories: Avastin Bevacizumab Breast Cancer Herceptin T-DM1 Trastuzumab

Curcumin, piperine could play role in preventing breast cancer.ANN ARBOR, Mich. — A new study finds that compounds derived from the spices turmeric and pepper could help prevent breast cancer by limiting the growth of stem cells, the small number of cells that fuel a tumor’s...

Published on 8 December 2009, 12:32

Categories: Breast Cancer Cancer stem cells Curcumin Piperine Spices Stem Cells Toxicity

Social isolation and related stress could contribute to human breast cancer susceptibility, according to research using a rat model designed at the University of Chicago to identify environmental contributions to cancer risk.The researchers found that isolation and stress result in a 3.3-fold...

Published on 7 December 2009, 14:45

Categories: Social isolation Stress Breast Cancer Psychology

Researchers have identified several genes whose spatial position inside the cell nucleus is altered in invasive breast cancer when compared to normal breast tissue. The findings suggest that cancer cells may have disease-specific, three-dimensional gene...

Published on 7 December 2009, 08:48

Categories: Genes Cell nucleus Breast Cancer HES5 Nucleus Cancer Cell Biology

CINCINNATI—Researchers at the University of Cincinnati (UC) have documented that the brain hormone serotonin is made in human breast cancer cells and functions abnormally, contributing to malignant growth.Researchers in the lab of Nelson Horseman, PhD, a professor in the department of molecular...

Published on 24 November 2009, 14:54

Categories: Serotonin Hormones Brain Hormones Breast Cancer Mood regulation SSRIs Selective serotonin reuptake inhibitors

Researchers at the University of Wisconsin-Madison School of Medicine and Public Health have eliminated cervical cancer in mice with two FDA-approved drugs currently used to treat breast cancer and osteoporosis.Published in this week's (Nov. 9) Proceedings of the National Academy of...

Published on 9 November 2009, 15:26

Categories: Cervical Cancer Drugs Estrogen Cervix Vagina Breast Cancer Osteoporosis HPV ER alpha

New Haven, Conn. — The right combination of estrogen and a selective estrogen receptor modulator (SERM), which blocks the effects of estrogen in breast tissue, could relieve menopause symptoms and cut breast cancer risk, Yale researchers report in an abstract presented at the American Society...

Published on 19 October 2009, 16:29

Categories: Menopause Hormones SERM Estrogen Breast Cancer Progestin

A new cancer gene has been discovered by a research group at the Sahlgrenska Academy. The gene causes an insidious form of glandular cancer usually in the head and neck and in women also in the breast. The discovery could lead to quicker and better diagnosis and more effective treatment.The study...

Published on 13 October 2009, 08:23

Categories: Adenoid cystic carcinoma Cancer MYB Fusion gene Breast Cancer Head Cancer Neck Cancer

Study looks at clinical trial that tested estrogen-plus-progestin combination.Women who developed new-onset breast tenderness after starting estrogen plus progestin hormone replacement therapy were at significantly higher risk for developing breast cancer than women on the combination therapy...

Published on 12 October 2009, 18:10

Categories: Estrogen Progestin Hormones Hormone replacement therapy Breast Cancer Breast tenderness Hormone Therapy

Scientists at the University of Toronto have developed a new "lab-on-a-chip" technique that analyses tiny samples of blood and breast tissue to identify women at risk of breast cancer much more quickly than ever before."The concentration of the hormone estrogen and its metabolites...

Published on 8 October 2009, 14:43

Categories: Breast Cancer Digital microfluidics Estrogen Hormones Lab-on-a-chip LOC

ROCHESTER, Minn. — Mayo Clinic researchers have found that certain structural features within breast tissue can indicate a woman's individual cancer risk. The findings appear online today in the Journal of Clinical Oncology.The study shows that acini (AS-ih-nye), the small...

Published on 5 October 2009, 15:25

Categories: Oncology Acini Breast Cancer Breast Tissue