APP News (6 articles)
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Potential New Drug Candidate Found for Alzheimer's DiseaseResearchers at the University of California, San Diego, the Medical University of South Carolina and American Life Science Pharmaceuticals of San Diego have demonstrated that oral administration of a cysteine protease inhibitor, E64d, not only reduces the build-up of β-amyloid (Aβ) in... Published on 31 May 2011, 14:40 |
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New Approach to Alzheimer’s TherapyDZNE and LMU researchers identify key target moleculeResearchers from the German Centre for Neurodegenerative Diseases (DZNE) and LMU Munich have shown that the ADAM10 protein can inhibit the formation of beta-amyloid, which is responsible for Alzheimer’s disease. ADAM10 acts like a pair of... Published on 1 August 2010, 15:49 |
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New Key Factor Identified in the Development of Alzheimer’s DiseaseInheritance of an extra copy of the gene ß-amyloid precursor protein, APP, in individuals with Down syndrome leads to the inevitable development of early onset Alzheimer's disease, known to be linked to the deposition of Amyloid ß peptide or Aß in the brain. However, a new study published... Published on 4 January 2010, 12:09 |
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APP – Good, Bad or Both?CHICAGO – New data about amyloid precursor protein, or APP, a protein implicated in development of Alzheimer’s disease, suggests it also may have a positive role -- directly affecting learning and memory during brain development. So is APP good or bad? Researchers at Georgetown University... Published on 18 October 2009, 16:25 |
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Novel Role of Protein in Generating Amyloid β PeptideA defining hallmark of Alzheimer’s disease is the accumulation of the amyloid β protein (Aβ), otherwise known as “senile plaques,” in the brain’s cortex and hippocampus, where memory consolidation occurs. Researchers at the University of California, San... Published on 27 April 2009, 16:45 |
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New target for medicine to combat Alzheimer’s: VIB scientists confirm protein’s key roleLeuven − VIB scientists connected to the Center for Human Heredity (K.U.Leuven) have demonstrated that a particular protein is extremely well suited to be a target for a new medicine against Alzheimer’s disease. Their research findings are being published in the authoritative journal... Published on 13 February 2009, 05:09 |
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