Strict Standards: Non-static method SEBenchmark::getInstance() should not be called statically in /home3/nextron/public_html/header.php on line 35

Strict Standards: Non-static method SESmarty::getInstance() should not be called statically in /home3/nextron/public_html/header.php on line 43

Strict Standards: Non-static method SEDatabase::getInstance() should not be called statically in /home3/nextron/public_html/header.php on line 96

Strict Standards: Non-static method SELanguage::info() should not be called statically in /home3/nextron/public_html/header.php on line 104

Strict Standards: Non-static method SELanguage::_init() should not be called statically in /home3/nextron/public_html/include/language/language.php on line 334

Strict Standards: Non-static method SELanguageStorage::getInstance() should not be called statically, assuming $this from incompatible context in /home3/nextron/public_html/include/language/language.php on line 156

Strict Standards: Declaration of SELanguageStorageMysql::edit() should be compatible with SELanguageStorage::edit() in /home3/nextron/public_html/include/language/storage/mysql.php on line 255

Strict Standards: Declaration of SELanguageStorageMysql::get() should be compatible with SELanguageStorage::get() in /home3/nextron/public_html/include/language/storage/mysql.php on line 255

Strict Standards: Non-static method SECore::getSettings() should not be called statically in /home3/nextron/public_html/header.php on line 107

Strict Standards: Non-static method SECache::getInstance() should not be called statically in /home3/nextron/public_html/include/class_core.php on line 28

Strict Standards: Non-static method SECacheStorage::getInstance() should not be called statically, assuming $this from incompatible context in /home3/nextron/public_html/include/cache/cache.php on line 66

Strict Standards: Non-static method SEDatabase::getInstance() should not be called statically in /home3/nextron/public_html/include/class_core.php on line 39

Strict Standards: Non-static method SECache::getInstance() should not be called statically, assuming $this from incompatible context in /home3/nextron/public_html/include/class_url.php on line 67

Strict Standards: Non-static method SECacheStorage::getInstance() should not be called statically, assuming $this from incompatible context in /home3/nextron/public_html/include/cache/cache.php on line 66

Strict Standards: Non-static method SEDatabase::getInstance() should not be called statically, assuming $this from incompatible context in /home3/nextron/public_html/include/class_url.php on line 78

Strict Standards: Non-static method SELanguage::_preload_multi() should not be called statically, assuming $this from incompatible context in /home3/nextron/public_html/include/class_datetime.php on line 35

Strict Standards: Non-static method SELanguage::_init() should not be called statically, assuming $this from incompatible context in /home3/nextron/public_html/include/language/language.php on line 529

Strict Standards: Non-static method SESession::getInstance() should not be called statically in /home3/nextron/public_html/header.php on line 125

Strict Standards: Non-static method SESessionStorage::getInstance() should not be called statically, assuming $this from incompatible context in /home3/nextron/public_html/include/session/session.php on line 49

Strict Standards: Declaration of SESessionStorageNone::register() should be compatible with SESessionStorage::register($options = Array) in /home3/nextron/public_html/include/session/storage/none.php on line 16

Strict Standards: Non-static method SEDatabase::getInstance() should not be called statically, assuming $this from incompatible context in /home3/nextron/public_html/include/session/session.php on line 600

Strict Standards: Non-static method SESession::getInstance() should not be called statically, assuming $this from incompatible context in /home3/nextron/public_html/include/class_user.php on line 509

Strict Standards: Non-static method SESession::getInstance() should not be called statically, assuming $this from incompatible context in /home3/nextron/public_html/include/class_admin.php on line 208

Strict Standards: Non-static method SELanguage::select() should not be called statically in /home3/nextron/public_html/header.php on line 181

Strict Standards: Non-static method SELanguage::_init() should not be called statically in /home3/nextron/public_html/include/language/language.php on line 234

Strict Standards: Non-static method SELanguage::info() should not be called statically in /home3/nextron/public_html/header.php on line 183

Strict Standards: Non-static method SELanguage::_init() should not be called statically in /home3/nextron/public_html/include/language/language.php on line 334

Strict Standards: Non-static method SELanguage::info() should not be called statically in /home3/nextron/public_html/header.php on line 189

Strict Standards: Non-static method SELanguage::_init() should not be called statically in /home3/nextron/public_html/include/language/language.php on line 334

Strict Standards: Non-static method SECore::getPlugins() should not be called statically in /home3/nextron/public_html/header.php on line 229

Strict Standards: Non-static method SECache::getInstance() should not be called statically in /home3/nextron/public_html/include/class_core.php on line 62

Strict Standards: Non-static method SECacheStorage::getInstance() should not be called statically, assuming $this from incompatible context in /home3/nextron/public_html/include/cache/cache.php on line 66

Strict Standards: Non-static method SEDatabase::getInstance() should not be called statically in /home3/nextron/public_html/include/class_core.php on line 73

Strict Standards: Declaration of rc_rssfeed::delete() should be compatible with rc_model::delete($id = NULL) in /home3/nextron/public_html/include/class_rssfeed.php on line 132

Deprecated: Assigning the return value of new by reference is deprecated in /home3/nextron/public_html/include/class_radcodes_rss.php on line 720

Deprecated: Assigning the return value of new by reference is deprecated in /home3/nextron/public_html/include/class_radcodes_rss.php on line 1087

Deprecated: Assigning the return value of new by reference is deprecated in /home3/nextron/public_html/include/class_radcodes_rss.php on line 1595

Deprecated: Assigning the return value of new by reference is deprecated in /home3/nextron/public_html/include/class_radcodes_rss.php on line 1636

Deprecated: Assigning the return value of new by reference is deprecated in /home3/nextron/public_html/include/class_radcodes_rss.php on line 1656

Deprecated: Assigning the return value of new by reference is deprecated in /home3/nextron/public_html/include/class_radcodes_rss.php on line 1756

Deprecated: Assigning the return value of new by reference is deprecated in /home3/nextron/public_html/include/class_radcodes_rss.php on line 1960

Deprecated: Assigning the return value of new by reference is deprecated in /home3/nextron/public_html/include/class_radcodes_rss.php on line 2358

Deprecated: Assigning the return value of new by reference is deprecated in /home3/nextron/public_html/include/class_radcodes_rss.php on line 2362

Deprecated: Assigning the return value of new by reference is deprecated in /home3/nextron/public_html/include/class_radcodes_rss.php on line 2366

Deprecated: Assigning the return value of new by reference is deprecated in /home3/nextron/public_html/include/class_radcodes_rss.php on line 2370

Deprecated: Assigning the return value of new by reference is deprecated in /home3/nextron/public_html/include/class_radcodes_rss.php on line 2418

Deprecated: Assigning the return value of new by reference is deprecated in /home3/nextron/public_html/include/class_radcodes_rss.php on line 2440

Deprecated: Assigning the return value of new by reference is deprecated in /home3/nextron/public_html/include/class_radcodes_rss.php on line 2445

Deprecated: Assigning the return value of new by reference is deprecated in /home3/nextron/public_html/include/class_radcodes_rss.php on line 2449

Deprecated: Assigning the return value of new by reference is deprecated in /home3/nextron/public_html/include/class_radcodes_rss.php on line 2453

Deprecated: Assigning the return value of new by reference is deprecated in /home3/nextron/public_html/include/class_radcodes_rss.php on line 2501

Deprecated: Assigning the return value of new by reference is deprecated in /home3/nextron/public_html/include/class_radcodes_rss.php on line 2523

Deprecated: Assigning the return value of new by reference is deprecated in /home3/nextron/public_html/include/class_radcodes_rss.php on line 2927

Deprecated: Assigning the return value of new by reference is deprecated in /home3/nextron/public_html/include/class_radcodes_rss.php on line 2935

Deprecated: Assigning the return value of new by reference is deprecated in /home3/nextron/public_html/include/class_radcodes_rss.php on line 2943

Deprecated: Assigning the return value of new by reference is deprecated in /home3/nextron/public_html/include/class_radcodes_rss.php on line 2951

Deprecated: Assigning the return value of new by reference is deprecated in /home3/nextron/public_html/include/class_radcodes_rss.php on line 2959

Deprecated: Assigning the return value of new by reference is deprecated in /home3/nextron/public_html/include/class_radcodes_rss.php on line 3300

Deprecated: Assigning the return value of new by reference is deprecated in /home3/nextron/public_html/include/class_radcodes_rss.php on line 3304

Deprecated: Assigning the return value of new by reference is deprecated in /home3/nextron/public_html/include/class_radcodes_rss.php on line 3308

Deprecated: Assigning the return value of new by reference is deprecated in /home3/nextron/public_html/include/class_radcodes_rss.php on line 3312

Deprecated: Assigning the return value of new by reference is deprecated in /home3/nextron/public_html/include/class_radcodes_rss.php on line 3373

Deprecated: Assigning the return value of new by reference is deprecated in /home3/nextron/public_html/include/class_radcodes_rss.php on line 3395

Deprecated: Assigning the return value of new by reference is deprecated in /home3/nextron/public_html/include/class_radcodes_rss.php on line 3434

Deprecated: Assigning the return value of new by reference is deprecated in /home3/nextron/public_html/include/class_radcodes_rss.php on line 3456

Deprecated: Assigning the return value of new by reference is deprecated in /home3/nextron/public_html/include/class_radcodes_rss.php on line 3461

Deprecated: Assigning the return value of new by reference is deprecated in /home3/nextron/public_html/include/class_radcodes_rss.php on line 3465

Deprecated: Assigning the return value of new by reference is deprecated in /home3/nextron/public_html/include/class_radcodes_rss.php on line 3469

Deprecated: Assigning the return value of new by reference is deprecated in /home3/nextron/public_html/include/class_radcodes_rss.php on line 3473

Deprecated: Assigning the return value of new by reference is deprecated in /home3/nextron/public_html/include/class_radcodes_rss.php on line 3783

Deprecated: Assigning the return value of new by reference is deprecated in /home3/nextron/public_html/include/class_radcodes_rss.php on line 3815

Deprecated: Assigning the return value of new by reference is deprecated in /home3/nextron/public_html/include/class_radcodes_rss.php on line 3845

Deprecated: Assigning the return value of new by reference is deprecated in /home3/nextron/public_html/include/class_radcodes_rss.php on line 3868

Deprecated: Assigning the return value of new by reference is deprecated in /home3/nextron/public_html/include/class_radcodes_rss.php on line 3879

Deprecated: Assigning the return value of new by reference is deprecated in /home3/nextron/public_html/include/class_radcodes_rss.php on line 3889

Deprecated: Assigning the return value of new by reference is deprecated in /home3/nextron/public_html/include/class_radcodes_rss.php on line 3911

Deprecated: Assigning the return value of new by reference is deprecated in /home3/nextron/public_html/include/class_radcodes_rss.php on line 3925

Deprecated: Assigning the return value of new by reference is deprecated in /home3/nextron/public_html/include/class_radcodes_rss.php on line 3952

Deprecated: Assigning the return value of new by reference is deprecated in /home3/nextron/public_html/include/class_radcodes_rss.php on line 3978

Deprecated: Assigning the return value of new by reference is deprecated in /home3/nextron/public_html/include/class_radcodes_rss.php on line 4167

Deprecated: Assigning the return value of new by reference is deprecated in /home3/nextron/public_html/include/class_radcodes_rss.php on line 4180

Deprecated: Assigning the return value of new by reference is deprecated in /home3/nextron/public_html/include/class_radcodes_rss.php on line 4201

Deprecated: Assigning the return value of new by reference is deprecated in /home3/nextron/public_html/include/class_radcodes_rss.php on line 4214

Deprecated: Assigning the return value of new by reference is deprecated in /home3/nextron/public_html/include/class_radcodes_rss.php on line 4242

Deprecated: Assigning the return value of new by reference is deprecated in /home3/nextron/public_html/include/class_radcodes_rss.php on line 4256

Deprecated: Assigning the return value of new by reference is deprecated in /home3/nextron/public_html/include/class_radcodes_rss.php on line 4278

Deprecated: Assigning the return value of new by reference is deprecated in /home3/nextron/public_html/include/class_radcodes_rss.php on line 4292

Deprecated: Assigning the return value of new by reference is deprecated in /home3/nextron/public_html/include/class_radcodes_rss.php on line 4496

Deprecated: Assigning the return value of new by reference is deprecated in /home3/nextron/public_html/include/class_radcodes_rss.php on line 4532

Deprecated: Assigning the return value of new by reference is deprecated in /home3/nextron/public_html/include/class_radcodes_rss.php on line 4568

Deprecated: Assigning the return value of new by reference is deprecated in /home3/nextron/public_html/include/class_radcodes_rss.php on line 4594

Deprecated: Assigning the return value of new by reference is deprecated in /home3/nextron/public_html/include/class_radcodes_rss.php on line 4623

Deprecated: Assigning the return value of new by reference is deprecated in /home3/nextron/public_html/include/class_radcodes_rss.php on line 4637

Deprecated: Assigning the return value of new by reference is deprecated in /home3/nextron/public_html/include/class_radcodes_rss.php on line 4668

Deprecated: Assigning the return value of new by reference is deprecated in /home3/nextron/public_html/include/class_radcodes_rss.php on line 4698

Deprecated: Assigning the return value of new by reference is deprecated in /home3/nextron/public_html/include/class_radcodes_rss.php on line 4851

Deprecated: Assigning the return value of new by reference is deprecated in /home3/nextron/public_html/include/class_radcodes_rss.php on line 4876

Deprecated: Assigning the return value of new by reference is deprecated in /home3/nextron/public_html/include/class_radcodes_rss.php on line 4908

Deprecated: Assigning the return value of new by reference is deprecated in /home3/nextron/public_html/include/class_radcodes_rss.php on line 4934

Deprecated: Assigning the return value of new by reference is deprecated in /home3/nextron/public_html/include/class_radcodes_rss.php on line 4988

Deprecated: Assigning the return value of new by reference is deprecated in /home3/nextron/public_html/include/class_radcodes_rss.php on line 5117

Deprecated: Assigning the return value of new by reference is deprecated in /home3/nextron/public_html/include/class_radcodes_rss.php on line 5153

Deprecated: Assigning the return value of new by reference is deprecated in /home3/nextron/public_html/include/class_radcodes_rss.php on line 5186

Deprecated: Assigning the return value of new by reference is deprecated in /home3/nextron/public_html/include/class_radcodes_rss.php on line 5217

Deprecated: Assigning the return value of new by reference is deprecated in /home3/nextron/public_html/include/class_radcodes_rss.php on line 5321

Deprecated: Assigning the return value of new by reference is deprecated in /home3/nextron/public_html/include/class_radcodes_rss.php on line 5353

Deprecated: Assigning the return value of new by reference is deprecated in /home3/nextron/public_html/include/class_radcodes_rss.php on line 5392

Deprecated: Assigning the return value of new by reference is deprecated in /home3/nextron/public_html/include/class_radcodes_rss.php on line 5428

Deprecated: Assigning the return value of new by reference is deprecated in /home3/nextron/public_html/include/class_radcodes_rss.php on line 5463

Deprecated: Assigning the return value of new by reference is deprecated in /home3/nextron/public_html/include/class_radcodes_rss.php on line 5498

Deprecated: Assigning the return value of new by reference is deprecated in /home3/nextron/public_html/include/class_radcodes_rss.php on line 5505

Deprecated: Assigning the return value of new by reference is deprecated in /home3/nextron/public_html/include/class_radcodes_rss.php on line 5790

Deprecated: Assigning the return value of new by reference is deprecated in /home3/nextron/public_html/include/class_radcodes_rss.php on line 5794

Deprecated: Assigning the return value of new by reference is deprecated in /home3/nextron/public_html/include/class_radcodes_rss.php on line 5798

Deprecated: Assigning the return value of new by reference is deprecated in /home3/nextron/public_html/include/class_radcodes_rss.php on line 5802

Deprecated: Assigning the return value of new by reference is deprecated in /home3/nextron/public_html/include/class_radcodes_rss.php on line 5850

Deprecated: Assigning the return value of new by reference is deprecated in /home3/nextron/public_html/include/class_radcodes_rss.php on line 5872

Deprecated: Assigning the return value of new by reference is deprecated in /home3/nextron/public_html/include/class_radcodes_rss.php on line 5877

Deprecated: Assigning the return value of new by reference is deprecated in /home3/nextron/public_html/include/class_radcodes_rss.php on line 5881

Deprecated: Assigning the return value of new by reference is deprecated in /home3/nextron/public_html/include/class_radcodes_rss.php on line 5885

Deprecated: Assigning the return value of new by reference is deprecated in /home3/nextron/public_html/include/class_radcodes_rss.php on line 5933

Deprecated: Assigning the return value of new by reference is deprecated in /home3/nextron/public_html/include/class_radcodes_rss.php on line 5955

Deprecated: Assigning the return value of new by reference is deprecated in /home3/nextron/public_html/include/class_radcodes_rss.php on line 6392

Deprecated: Assigning the return value of new by reference is deprecated in /home3/nextron/public_html/include/class_radcodes_rss.php on line 7588

Deprecated: Assigning the return value of new by reference is deprecated in /home3/nextron/public_html/include/class_radcodes_rss.php on line 7649

Deprecated: Assigning the return value of new by reference is deprecated in /home3/nextron/public_html/include/class_radcodes_rss.php on line 7730

Deprecated: Assigning the return value of new by reference is deprecated in /home3/nextron/public_html/include/class_radcodes_rss.php on line 12921

Deprecated: Assigning the return value of new by reference is deprecated in /home3/nextron/public_html/include/class_radcodes_rss.php on line 12986

Deprecated: Assigning the return value of new by reference is deprecated in /home3/nextron/public_html/include/class_radcodes_rss.php on line 13011

Deprecated: Assigning the return value of new by reference is deprecated in /home3/nextron/public_html/include/class_radcodes_rss.php on line 13574

Strict Standards: Non-static method SELanguage::_preload_multi() should not be called statically in /home3/nextron/public_html/header_rssfeed.php on line 10

Strict Standards: Non-static method SELanguage::_init() should not be called statically in /home3/nextron/public_html/include/language/language.php on line 529

Strict Standards: Non-static method rc_toolkit::get_setting() should not be called statically in /home3/nextron/public_html/header_rssfeed.php on line 14

Strict Standards: Non-static method rc_toolkit::owner_level() should not be called statically in /home3/nextron/public_html/header_rssfeed.php on line 25

Strict Standards: Non-static method SELanguage::_preload_multi() should not be called statically in /home3/nextron/public_html/header_article.php on line 10

Strict Standards: Non-static method SELanguage::_init() should not be called statically in /home3/nextron/public_html/include/language/language.php on line 529

Strict Standards: Non-static method SE_Hook::register() should not be called statically in /home3/nextron/public_html/header_article.php on line 66

Strict Standards: Non-static method SE_Hook::create() should not be called statically in /home3/nextron/public_html/include/class_hook.php on line 151

Strict Standards: Non-static method SE_Hook::register() should not be called statically in /home3/nextron/public_html/header_article.php on line 67

Strict Standards: Non-static method SE_Hook::create() should not be called statically in /home3/nextron/public_html/include/class_hook.php on line 151

Strict Standards: Non-static method SELanguage::_preload() should not be called statically in /home3/nextron/public_html/header_event.php on line 15

Strict Standards: Non-static method SELanguage::_init() should not be called statically in /home3/nextron/public_html/include/language/language.php on line 559

Strict Standards: Non-static method SE_Hook::register() should not be called statically in /home3/nextron/public_html/header_event.php on line 67

Strict Standards: Non-static method SE_Hook::create() should not be called statically in /home3/nextron/public_html/include/class_hook.php on line 151

Strict Standards: Non-static method SE_Hook::register() should not be called statically in /home3/nextron/public_html/header_event.php on line 69

Strict Standards: Non-static method SE_Hook::create() should not be called statically in /home3/nextron/public_html/include/class_hook.php on line 151

Strict Standards: Non-static method SE_Hook::register() should not be called statically in /home3/nextron/public_html/header_event.php on line 71

Strict Standards: Non-static method SE_Hook::create() should not be called statically in /home3/nextron/public_html/include/class_hook.php on line 151

Strict Standards: Non-static method SE_Hook::register() should not be called statically in /home3/nextron/public_html/header_event.php on line 73

Strict Standards: Non-static method SE_Hook::create() should not be called statically in /home3/nextron/public_html/include/class_hook.php on line 151

Strict Standards: Non-static method SE_Hook::register() should not be called statically in /home3/nextron/public_html/header_event.php on line 75

Strict Standards: Non-static method SE_Hook::create() should not be called statically in /home3/nextron/public_html/include/class_hook.php on line 151

Strict Standards: Non-static method SELanguage::_preload() should not be called statically in /home3/nextron/public_html/header_group.php on line 14

Strict Standards: Non-static method SELanguage::_init() should not be called statically in /home3/nextron/public_html/include/language/language.php on line 559

Strict Standards: Non-static method SE_Hook::register() should not be called statically in /home3/nextron/public_html/header_group.php on line 82

Strict Standards: Non-static method SE_Hook::create() should not be called statically in /home3/nextron/public_html/include/class_hook.php on line 151

Strict Standards: Non-static method SE_Hook::register() should not be called statically in /home3/nextron/public_html/header_group.php on line 85

Strict Standards: Non-static method SE_Hook::create() should not be called statically in /home3/nextron/public_html/include/class_hook.php on line 151

Strict Standards: Non-static method SE_Hook::register() should not be called statically in /home3/nextron/public_html/header_group.php on line 88

Strict Standards: Non-static method SE_Hook::create() should not be called statically in /home3/nextron/public_html/include/class_hook.php on line 151

Strict Standards: Non-static method SELanguage::_preload() should not be called statically in /home3/nextron/public_html/header_classified.php on line 15

Strict Standards: Non-static method SELanguage::_init() should not be called statically in /home3/nextron/public_html/include/language/language.php on line 559

Strict Standards: Non-static method SE_Hook::register() should not be called statically in /home3/nextron/public_html/header_classified.php on line 64

Strict Standards: Non-static method SE_Hook::create() should not be called statically in /home3/nextron/public_html/include/class_hook.php on line 151

Strict Standards: Non-static method SE_Hook::register() should not be called statically in /home3/nextron/public_html/header_classified.php on line 66

Strict Standards: Non-static method SE_Hook::create() should not be called statically in /home3/nextron/public_html/include/class_hook.php on line 151

Strict Standards: Non-static method SE_Hook::register() should not be called statically in /home3/nextron/public_html/header_classified.php on line 68

Strict Standards: Non-static method SE_Hook::create() should not be called statically in /home3/nextron/public_html/include/class_hook.php on line 151

Strict Standards: Non-static method SE_Hook::register() should not be called statically in /home3/nextron/public_html/header_radcodes.php on line 10

Strict Standards: Non-static method SE_Hook::create() should not be called statically in /home3/nextron/public_html/include/class_hook.php on line 151

Strict Standards: Non-static method SELanguage::_preload_multi() should not be called statically in /home3/nextron/public_html/header_vid.php on line 15

Strict Standards: Non-static method SELanguage::_init() should not be called statically in /home3/nextron/public_html/include/language/language.php on line 529

Strict Standards: Non-static method SE_Hook::register() should not be called statically in /home3/nextron/public_html/header_vid.php on line 44

Strict Standards: Non-static method SE_Hook::create() should not be called statically in /home3/nextron/public_html/include/class_hook.php on line 151

Strict Standards: Non-static method SE_Hook::register() should not be called statically in /home3/nextron/public_html/header_vid.php on line 45

Strict Standards: Non-static method SE_Hook::create() should not be called statically in /home3/nextron/public_html/include/class_hook.php on line 151

Strict Standards: Non-static method SELanguage::_preload_multi() should not be called statically in /home3/nextron/public_html/header_page.php on line 11

Strict Standards: Non-static method SELanguage::_init() should not be called statically in /home3/nextron/public_html/include/language/language.php on line 529

Strict Standards: Non-static method SELanguage::_preload_multi() should not be called statically in /home3/nextron/public_html/header_gmap.php on line 10

Strict Standards: Non-static method SELanguage::_init() should not be called statically in /home3/nextron/public_html/include/language/language.php on line 529

Strict Standards: Non-static method SE_Hook::exists() should not be called statically in /home3/nextron/public_html/header.php on line 298

Strict Standards: Non-static method SE_Hook::create() should not be called statically in /home3/nextron/public_html/include/class_hook.php on line 246

Strict Standards: Non-static method SECache::getInstance() should not be called statically, assuming $this from incompatible context in /home3/nextron/public_html/include/class_user.php on line 280

Strict Standards: Non-static method SECacheStorage::getInstance() should not be called statically, assuming $this from incompatible context in /home3/nextron/public_html/include/cache/cache.php on line 66

Strict Standards: Non-static method SEDatabase::getInstance() should not be called statically, assuming $this from incompatible context in /home3/nextron/public_html/include/class_user.php on line 291

Strict Standards: Non-static method SECache::getInstance() should not be called statically, assuming $this from incompatible context in /home3/nextron/public_html/include/class_user.php on line 320

Strict Standards: Non-static method SECacheStorage::getInstance() should not be called statically, assuming $this from incompatible context in /home3/nextron/public_html/include/cache/cache.php on line 66

Strict Standards: Non-static method SEDatabase::getInstance() should not be called statically, assuming $this from incompatible context in /home3/nextron/public_html/include/class_user.php on line 331

Strict Standards: Non-static method SECache::getInstance() should not be called statically, assuming $this from incompatible context in /home3/nextron/public_html/include/class_user.php on line 200

Strict Standards: Non-static method SECacheStorage::getInstance() should not be called statically, assuming $this from incompatible context in /home3/nextron/public_html/include/cache/cache.php on line 66

Strict Standards: Non-static method SEDatabase::getInstance() should not be called statically, assuming $this from incompatible context in /home3/nextron/public_html/include/class_user.php on line 211

Strict Standards: Non-static method SECache::getInstance() should not be called statically, assuming $this from incompatible context in /home3/nextron/public_html/include/class_user.php on line 240

Strict Standards: Non-static method SECacheStorage::getInstance() should not be called statically, assuming $this from incompatible context in /home3/nextron/public_html/include/cache/cache.php on line 66

Strict Standards: Non-static method SEDatabase::getInstance() should not be called statically, assuming $this from incompatible context in /home3/nextron/public_html/include/class_user.php on line 251

Strict Standards: Non-static method SELanguage::_preload() should not be called statically, assuming $this from incompatible context in /home3/nextron/public_html/include/class_user.php on line 179

Strict Standards: Non-static method SELanguage::_init() should not be called statically, assuming $this from incompatible context in /home3/nextron/public_html/include/language/language.php on line 559

Strict Standards: Non-static method SECore::getLanguages() should not be called statically in /home3/nextron/public_html/footer.php on line 14

Strict Standards: Non-static method SECache::getInstance() should not be called statically in /home3/nextron/public_html/include/class_core.php on line 96

Strict Standards: Non-static method SECacheStorage::getInstance() should not be called statically, assuming $this from incompatible context in /home3/nextron/public_html/include/cache/cache.php on line 66

Strict Standards: Non-static method SELanguage::_languages() should not be called statically in /home3/nextron/public_html/include/class_core.php on line 110

Strict Standards: Non-static method SELanguage::_init() should not be called statically in /home3/nextron/public_html/include/language/language.php on line 366

Strict Standards: Non-static method SE_Hook::exists() should not be called statically in /home3/nextron/public_html/footer.php on line 29

Strict Standards: Non-static method SE_Hook::create() should not be called statically in /home3/nextron/public_html/include/class_hook.php on line 246

Strict Standards: Non-static method SE_Hook::exists() should not be called statically in /home3/nextron/public_html/footer.php on line 32

Strict Standards: Non-static method SE_Hook::create() should not be called statically in /home3/nextron/public_html/include/class_hook.php on line 246

Strict Standards: Non-static method SE_Hook::call() should not be called statically in /home3/nextron/public_html/footer.php on line 32

Strict Standards: Non-static method SE_Hook::create() should not be called statically in /home3/nextron/public_html/include/class_hook.php on line 272

Strict Standards: Non-static method SELanguage::info() should not be called statically in /home3/nextron/public_html/footer.php on line 58

Strict Standards: Non-static method SELanguage::_init() should not be called statically in /home3/nextron/public_html/include/language/language.php on line 334

Strict Standards: Non-static method SELanguage::_preload_multi() should not be called statically, assuming $this from incompatible context in /home3/nextron/public_html/include/smarty/templates_c/%%86^861^861EA998%%article.tpl.php on line 6

Strict Standards: Non-static method SELanguage::_init() should not be called statically, assuming $this from incompatible context in /home3/nextron/public_html/include/language/language.php on line 529

Strict Standards: Non-static method SELanguage::load() should not be called statically, assuming $this from incompatible context in /home3/nextron/public_html/include/smarty/templates_c/%%86^861^861EA998%%article.tpl.php on line 7

Strict Standards: Non-static method SELanguage::_init() should not be called statically, assuming $this from incompatible context in /home3/nextron/public_html/include/language/language.php on line 686

Strict Standards: Non-static method SELanguage::_init() should not be called statically, assuming $this from incompatible context in /home3/nextron/public_html/include/language/storage.php on line 192

Strict Standards: Non-static method SECache::getInstance() should not be called statically, assuming $this from incompatible context in /home3/nextron/public_html/include/language/storage.php on line 193

Strict Standards: Non-static method SECacheStorage::getInstance() should not be called statically, assuming $this from incompatible context in /home3/nextron/public_html/include/cache/cache.php on line 66

Strict Standards: Only variables should be passed by reference in /home3/nextron/public_html/include/language/storage/mysql.php on line 177

Strict Standards: Non-static method SELanguage::_preload_multi() should not be called statically, assuming $this from incompatible context in /home3/nextron/public_html/include/smarty/templates_c/%%05^053^053AB562%%header_article2.tpl.php on line 4

Strict Standards: Non-static method SELanguage::_init() should not be called statically, assuming $this from incompatible context in /home3/nextron/public_html/include/language/language.php on line 529

Strict Standards: Non-static method SELanguage::load() should not be called statically, assuming $this from incompatible context in /home3/nextron/public_html/include/smarty/templates_c/%%05^053^053AB562%%header_article2.tpl.php on line 5

Strict Standards: Non-static method SELanguage::_init() should not be called statically, assuming $this from incompatible context in /home3/nextron/public_html/include/language/language.php on line 686

Strict Standards: Non-static method SELanguage::_init() should not be called statically, assuming $this from incompatible context in /home3/nextron/public_html/include/language/storage.php on line 169

Strict Standards: Non-static method SECache::getInstance() should not be called statically, assuming $this from incompatible context in /home3/nextron/public_html/include/language/storage.php on line 170

Strict Standards: Non-static method SECacheStorage::getInstance() should not be called statically, assuming $this from incompatible context in /home3/nextron/public_html/include/cache/cache.php on line 66
Vitamin K May Protect Against Developing Non-Hodgkin Lymphoma, Say Mayo Clinic Researchers - <br /> <b>Strict Standards</b>: Non-static method SELanguage::_get() should not be called statically, assuming $this from incompatible context in <b>/home3/nextron/public_html/include/smarty/templates_c/%%05^053^053AB562%%header_article2.tpl.php</b> on line <b>16</b><br /> <br /> <b>Strict Standards</b>: Non-static method SELanguage::_init() should not be called statically, assuming $this from incompatible context in <b>/home3/nextron/public_html/include/language/language.php</b> on line <b>614</b><br /> insciences
Strict Standards: Non-static method SELanguage::_preload_multi() should not be called statically, assuming $this from incompatible context in /home3/nextron/public_html/include/smarty/templates_c/%%87^870^870F1A81%%headerx.tpl.php on line 6

Strict Standards: Non-static method SELanguage::_init() should not be called statically, assuming $this from incompatible context in /home3/nextron/public_html/include/language/language.php on line 529

Strict Standards: Non-static method SELanguage::load() should not be called statically, assuming $this from incompatible context in /home3/nextron/public_html/include/smarty/templates_c/%%87^870^870F1A81%%headerx.tpl.php on line 7

Strict Standards: Non-static method SELanguage::_init() should not be called statically, assuming $this from incompatible context in /home3/nextron/public_html/include/language/language.php on line 686
Keyword Tag Sort by


Categories: Non-Hodgkin lymphoma Vitamin K Cancer Immune System Vitamins Phylloquinone Vitamin K1

Vitamin K May Protect Against Developing Non-Hodgkin Lymphoma, Say Mayo Clinic Researchers

WASHINGTON — In the first study of vitamin K and Non-Hodgkin lymphoma risk, researchers at the Mayo Clinic campus in Minnesota have found that people who have higher intakes of vitamin K from their diet have a lower risk of developing Non-Hodgkin lymphoma. Non-Hodgkin Lymphoma is a cancer of the immune system and is the most common hematologic malignancy in the United States.

At the 101st Annual Meeting of the American Association for Cancer Research (AACR), the researchers report that the risk of developing Non-Hodgkin lymphoma was approximately 45 percent lower for participants who had vitamin K intakes in the top quartile of intake in the study (>108 ug/day), compared to participants who had intakes in the bottom quartile (<39 ug/day). This association remained after accounting for other factors such as age, sex, education, obesity, smoking, alcohol use and intake of foods with high amounts of antioxidants.

Vitamin K is a fat-soluble vitamin and is derived from either plants (phylloquinone or vitamin K1) or bacterial synthesis. This study estimated intake of the plant form of vitamin K from diet and supplement use. The most common sources of vitamin K1 in the diet include leaf lettuce and spinach, with smaller amounts found in other vegetables, vegetable oils and some fruits.

Researchers at the Mayo Comprehensive Cancer Center are studying the connection between diet and Non-Hodgkin lymphoma risk, and they became interested in a potential role for vitamin K. While vitamin K is best known for its essential function in several proteins involved in blood clotting (the name of the vitamin is derived from the German word "Koagulations"), it also appears to be important in other biological processes, including inhibition of inflammatory cytokines thought to play a role in Non-Hodgkin lymphoma, as well as pathways involved in cell cycle arrest and cell death.

"These results are provocative, since they are the first work we have done on the connection between vitamin K and Non-Hodgkin lymphoma, and this is a fairly strong protective effect," says the study's lead investigator, James Cerhan, M.D., Ph.D., a cancer epidemiologist. "However, as with all new findings, this will need to be replicated in other studies."

The Mayo study enrolled 603 patients who were newly diagnosed with Non-Hodgkin lymphoma as well as 1,007 matched cancer-free "control" participants. Researchers asked the participants to answer a food questionnaire about their usual intake of over 120 food items two years prior to their cancer diagnosis or enrollment into the study (controls). They also asked about use of a variety of supplements. Vitamin K intake was estimated from this data.

While there was a clear trend showing that a greater intake of vitamin K from dietary sources was associated with a lower risk of Non-Hodgkin lymphoma, the use of vitamin K supplements presented a slightly different picture. Increasing intake of vitamin K from supplements did protect against Non-Hodgkin lymphoma, but reached a point where the highest intake offered no reduction in risk. "The significance of this finding is unclear," notes Dr. Cerhan, "but suggests that taking high doses of supplements is unlikely to be helpful." Dr. Cerhan also notes that people taking certain oral anticoagulants or seizure medications should closely follow their physician's dietary recommendations with respect to vitamin K intake, since vitamin K can interfere with these drugs.

"Whether the protective effect we observed is due to vitamin K intake, or some other dietary or lifestyle exposure, cannot be definitely assessed in this study," notes Dr. Cerhan. "But these findings add to a lot of other data that support a diet that includes plenty of green leafy vegetables in order to prevent many cancers as well as other diseases."

The study was funded by the National Cancer Institute.

Contact: Karl Oestreich, Tel: 507-284-5005, Email: newsbureau@mayo.edu

Source: Mayo Clinic

Related News:

Protein that accelerates age, brakes cancer 11 August 2013, 12:57
Prelamin A protein causes accelerated ageing disorders and also prevents the spread of cancer...

Study IDs key protein for cell death 16 May 2013, 04:32
Findings may offer a new way to kill cancer cells by forcing them into an alternative...

Mapping of cancer cell fuel pumps paves the way for new drugs 29 April 2013, 03:26
For the first time, researchers at Karolinska Institutet have managed to obtain detailed images...

Understanding Abnormal Proteins in Degenerative Diseases 22 April 2013, 07:55
New IBN Peptides May Help Researchers Combat Alzheimer’s, Diabetes and...

Sensor of bacteria and viruses on high alert at the site of action 16 January 2013, 05:51
Researchers show: Sophisticated transport system helps immune cells quickly detect...

Old anti-psychotics with a new, promising effect in cancer therapy 11 December 2012, 03:07
Neuherberg-- Scientists at the Helmholtz Zentrum München and their cooperation partners have...

Single gene defect wipes out immunity 10 December 2012, 09:51
Gene knockout stops immune cell development.Researchers at the Wellcome Trust Sanger Institute...

A*STAR Scientists Identify Potential Drug Target For Inflammatory... 21 November 2012, 03:24
This discovery holds the potential to reduce healthcare costs for many common inflammatory...

Gene switch important in cancer discovered 2 November 2012, 03:10
Scientists at Karolinska Institutet in Sweden and the University of Helsinki in Finland have...

Obesity Promotes Tumor Growth Regardless of Diet 15 October 2012, 03:37
Presence of fat tissue-derived cells in tumors is related to increased tumor growth. The...

Sign up for daily newsletter

Subscribe to daily Science News
(a free e-mail delivery powered by Google)

Top Categories



Strict Standards: Non-static method SELanguage::load() should not be called statically, assuming $this from incompatible context in /home3/nextron/public_html/include/smarty/templates_c/%%47^479^479B3B2F%%insciences.tpl.php on line 4

Strict Standards: Non-static method SELanguage::_init() should not be called statically, assuming $this from incompatible context in /home3/nextron/public_html/include/language/language.php on line 686

image

We have launched our peer- reviewed, Open-access journal: Insciences Journal

Recently added

27.11.12
Consequential Life Cycle Assessment of Nitrogen Fertilisers Based on Biomass – a Swedish perspective

08.11.12
From Molecular Hollows to Imprinting Strategies – Mass-Sensitive Devices in Host-Guest Chemistry

26.04.12
CdSe/ZnSe Quantum-Dot Semiconductor Optical Amplifiers

23.03.12
Screen-printed Electrochemical Sensors and Biosensors for Monitoring Metal Pollutants


 
 

Strict Standards: Non-static method SELanguage::load() should not be called statically, assuming $this from incompatible context in /home3/nextron/public_html/include/smarty/templates_c/%%76^762^76224BF7%%footerx.tpl.php on line 6

Strict Standards: Non-static method SELanguage::_init() should not be called statically, assuming $this from incompatible context in /home3/nextron/public_html/include/language/language.php on line 686