Keyword Tag Sort by


Categories: Diseases Topical Endoscopic Fundal Imaging Ophthalmology

New monitor for eye disease

The monitoring and treatment of eye diseases that may cause blindness has taken a big leap forward, thanks to a new imaging technique that takes high quality colour photographs of the whole retina.

Using the new technique called ‘TEFI’ (Topical Endoscopic Fundal Imaging), Professor Andrew Dick, David Copland and the team from the University of Bristol’s Academic Unit of Ophthalmology, monitored changes in mice retina over time, without distress to the animals or the need for anesthesia.

The study focused on a condition in mice similar to human posterior uveitis, an inflammation that affects the back of the eye and which can be difficult to monitor using existing techniques. TEFI allowed the researchers to see changes to the eye that were previously undetectable.

 “TEFI enhances our monitoring of clinical disease in a rapid and non-invasive fashion,” Copland said. “It will aid in the design of experimental protocols according to clinical observations.”

Professor Dick added: “Combined TEFI and histological methods enable the observation of clinical features and severity of disease, but information regarding the dynamics, phenotype, function and quantity of cellular traffic through the eye is only provided through detailed analysis of cell populations present in the eye at various stages of disease progression.”

The study, “The Clinical Time-Course of Experimental Autoimmune Uveoretinitis Using Topical Endoscopic Fundal Imaging with Histologic and Cellular Infiltrate Correlation,” was published this week in Investigative Ophthalmology and Visual Science. It featured the use of Topical Endoscopic Fundal Imaging (TEFI), a technique that uses an endoscope with parallel illumination and observation channels connected to a digital camera.

 

Contact: Cherry Lewis for further information.
Source: University of Bristol

Related News:

New data among 200 Lucentis® abstracts at ARVO show low number of... 10 May 2012, 04:49
Data from key studies highlight the value of individualized therapy and reinforce...

Photoreceptor Transplant Restores Vision in Mice 19 April 2012, 03:27
Scientists from the UCL Institute of Ophthalmology have shown for the first time that...

Stem Cells Can Repair a Damaged Cornea 2 February 2012, 05:22
A new cornea may be the only way to prevent a patient going blind – but there is a shortage of...

Vitamin D could combat the effects of ageing in eyes 16 January 2012, 06:19
Researchers funded by the Biotechnology and Biological Sciences Research Council (BBSRC) have...

Study Identifies Genetic Basis of Human Metabolic Individuality 27 October 2011, 05:04
Research May Lead to Highly Targeted, Individualized TherapiesNEW YORK — In what is so far the...

Blindness Recovery In Sight 20 April 2011, 09:49
Prospects for recovery of lost vision have brightened with the release of new scientific...

One Donor Cornea, Two Patients Helped 2 February 2011, 06:36
New surgical approach may help meet demand for donor corneas, says study in February’s...

Visionary stem cell technique offers new potential to treat blindness 22 September 2010, 05:41
Scientists funded by the Medical Research Council (MRC) are pioneering a stem cell treatment to...

UCSD Scientists Find Gas Pedal - And Brake - for Uncontrolled Cell... 2 August 2010, 14:01
Discoveries offer promising new way to treat wide array of diseases and conditions.Researchers...

UCLA Researchers Show How World's Smallest 'Coffee... 5 May 2010, 15:58
The field of biosensing has recently found an unlikely partner in the quest for increased...