Keyword Tag Sort by


Categories: Audiology Brain Cochlear Trauma Neural circuitry Neuroscience Tinnitus Ventral Cochlear Nucleus

New Link in Tinnitus Research

Researchers at The University of Western Australia have shown changes in a part of the brain previously not known to be involved in tinnitus generation. 

The nerve cell types and the chemistry of the neural circuitry in this part of the brain differ subtly from those other parts of the brain previously thought to be involved. This means the results published in The Journal of Neuroscience could be potentially important for the future development of drug treatments.

Tinnitus is a potentially debilitating disorder of hearing which is characterised by the perception of non-existent sounds, usually roaring, hissing or ringing in the ears.

The changes in the brain that cause tinnitus are poorly understood.  It is clear however that alterations in nerve cell electrical behaviour must underlie the abnormal "phantom" perception of sound that is experienced by tinnitus sufferers.

For many years, the exact site in the brain where this abnormal nerve cell behaviour occurs has been a contentious issue.

The research, performed by student Darryl Vogler, Professor Donald Robertson and Associate Professor Wilhelmina Mulders, has developed a reliable animal model which can induce tinnitus and also measure brain cell activity.

"This is an important step toward further research in this area," Associate Professor Mulders said.

"If we can establish a direct link between this increased brain cell activity and tinnitus we may be able to move a step closer to finding a way to treat tinnitus."

The paper titled Hyperactivity in the Ventral Cochlear Nucleus after Cochlear Trauma concludes that hyperactivity in this part of the brainstem therefore needs to be considered in relation to further neural research into tinnitus.

Contact: Janine MacDonald, UWA Public Affairs, Tel: (+61 8)  6488 5563, Email: janine.macdonald@uwa.edu.au

Source: The University of Western Australia

Photos (1)  [ view all photos ]


Audiology group. Source: The University of Western Australia

Related News:

Research discovers link between epilepsy and autism 16 May 2013, 04:51
Our researchers have found a previously undiscovered link between epileptic seizures and the...

Gladstone Scientists Identify Key Biological Mechanism in Multiple... 4 December 2012, 00:34
Cutting-edge imaging study finds potential new target to combat disease.SAN FRANCISCO,...

Plaque Build-up in Your Brain May Be More Harmful than Having... 17 October 2012, 04:12
MINNEAPOLIS – A new study shows that having a high amount of beta amyloid or "plaques" in the...

New analysis indicates that Novartis drug Gilenya shows significant... 12 October 2012, 03:53
New analysis of two large Phase III studies demonstrates a significant early treatment...

UCSF Study Shows Evidence that Transplanted Neural Stem Cells... 10 October 2012, 16:12
Phase I Investigation Demonstrates Signs of Engraftment and Safety at One Year.A Phase I...

UCLA scientists discover sleeping brain behaves as if it's... 8 October 2012, 04:38
UCLA researchers have for the first time measured the activity of a brain region known to be...

Penn Researchers Create a Universal Map of Vision in the Human Brain 4 October 2012, 12:36
New Technology Confirms "Timeless" Diagram Drafted by WW1 Neurologist.PHILADELPHIA — Nearly 100...

New Insights on Control of Pituitary Hormone Outside of Brain has... 2 October 2012, 04:23
PHILADELPHIA — The hormone prolactin is produced by the pituitary gland in the brain and then...

Genetic Atlas of Human Brain Could Lead to Better Treatments 19 September 2012, 14:38
Research into neurodegenerative diseases could be helped by a project that has shown for the...

Study Shows Brain Function Differences in Women with Anorexia 17 September 2012, 05:28
A new study published in Social Cognitive and Affective Neuroscience by researchers at the Center...

Credits / Source:

Audiology group. Source: The University of Western Australia